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v3.25.2

Segment Information - Financial Information (Details) - USD ($) $ in Millions | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2025 | Jun. 30, 2024 | Jun. 30, 2025 | Jun. 30, 2024
Segment Reporting Information [Line Items] |  |  |  |
Revenue | $ 22.4 | $ 76.5 | $ 211.2 | $ 101.8
Less: |  |  |  |
Total research and development expense | 68.6 | 93.7 | 159.4 | 178.0
General and administrative expense | 25.3 | 31.3 | 51.9 | 55.6
Income tax expense | (0.3) | 0.2 | (0.2) | 0.3
Interest income, net | 10.3 | 13.6 | 22.0 | 27.6
Segment net (loss) income | (61.2) | (35.2) | 21.7 | (104.6)
Reportable Segment |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Revenue | 22.4 | 76.5 | 211.2 | 101.8
Less: |  |  |  |
Non program-specific external expense | 11.1 | 13.5 | 25.0 | 29.6
Compensation and related personnel expense (including stock-based compensation) | 28.4 | 36.3 | 65.3 | 74.6
Other research and development expense | 4.3 | 3.2 | 7.4 | 6.2
Total research and development expense | 68.6 | 93.7 | 159.4 | 178.0
General and administrative expense | 25.3 | 31.3 | 51.9 | 55.6
Other segment expense, net | 0.3 | 0.1 | 0.4 | 0.1
Income tax expense | (0.3) | 0.2 | (0.2) | 0.3
Interest income, net | 10.3 | 13.6 | 22.0 | 27.6
Segment net (loss) income | (61.2) | (35.2) | 21.7 | (104.6)
Reportable Segment | Vepdegestrant ARV-471 |  |  |  |
Less: |  |  |  |
Program-specific external expense | 15.1 | 25.1 | 39.2 | 44.1
Reportable Segment | ARV-102 |  |  |  |
Less: |  |  |  |
Program-specific external expense | 3.8 | 1.7 | 10.3 | 3.0
Reportable Segment | ARV-393 |  |  |  |
Less: |  |  |  |
Program-specific external expense | 2.5 | 1.7 | 5.1 | 2.9
Reportable Segment | ARV-806 |  |  |  |
Less: |  |  |  |
Program-specific external expense | 1.7 | 0.2 | 2.6 | 0.3
Reportable Segment | Bavdegalutamide (ARV-110) |  |  |  |
Less: |  |  |  |
Program-specific external expense | 0.9 | 2.5 | 2.0 | 4.1
Reportable Segment | Luxdegalutamide (ARV-766) |  |  |  |
Less: |  |  |  |
Program-specific external expense | 0.0 | 9.5 | 0.0 | 13.2
Reportable Segment | Other programs |  |  |  |
Less: |  |  |  |
Program-specific external expense | $ 0.8 | $ 0.0 | $ 2.5 | $ 0.0

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