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Equity (Tables)

12 Months Ended

Dec. 31, 2025

Share-Based Payment Arrangement [Abstract]

Schedule of Assumptions Used to Determine Fair Value of Stock Options Granted

The fair value of the stock options granted during each of the years ended December 31, 2025, 2024 and 2023 was determined using the Black-Scholes option pricing model at the grant date with the following range of assumptions:

			Year ended December 31,
			2025									2024												2023
Expected volatility			72.1% - 80.4%			(1)						72.0% - 75.6%						(1)						71.3% - 75.0%
Expected term (years)			5.5 - 5.7			(2)						5.4 - 5.5						(2)						5.5 - 7.0
Risk free interest rate			3.7% - 4.4%			(3)						3.5% - 4.6%						(3)						3.4% - 4.8%
Expected dividend yield			0		%							0		%										0		%
Exercise price			$6.61 - $17.70									$24.19 - $47.00												$16.21 - $36.27

(1)    Expected volatility is calculated by utilizing the Company's historical volatility of its stock price over a period equal to the expected term.

(2)    Expected term is calculated based on the Company's historical experience.

(3)     Risk free interest rate is based on an interpolation of U.S. Treasury rates to reflect the expected term at the date of grant.

Schedule of Stock Option Activity

A summary of the stock option activity under the 2018 Plan as of December 31, 2025 is presented below. Included in the table are stock options granted to employees, directors and consultants under the 2018 Plan, as well as options to purchase 255,611 shares of common stock granted to certain employees pursuant to the Nasdaq inducement grant exception in accordance with Nasdaq Listing Rule 5635(c)(4).

(dollars in millions, except weighted-average exercise price)						Options						Weighted-Average Exercise Price						Weighted-Average Remaining Contractual Term (Years)						Aggregate Intrinsic Value
Outstanding as of December 31, 2024						7,892,330						$	44.16					6.7						$	3.2
Granted						2,253,860						$	12.41
Forfeited						(1,515,115)						$	46.07
Outstanding as of December 31, 2025						8,631,075						$	35.89					6.5						$	5.3
Vested and exercisable as of December 31, 2025						5,607,194						$	44.41					5.3						$	—
Vested and expected to vest as of December 31, 2025						8,304,964						$	36.55					6.4						$	4.9

Schedule of Restricted Stock Grant Activity

A summary of restricted stock unit ("RSU") activity under the 2018 Plan for the year ended December 31, 2025 is presented below. Included in the table are RSUs granted to employees and directors under the 2018 Plan, as well as RSUs representing 170,365 shares of common stock granted to certain employees pursuant to the Nasdaq inducement grant exception in accordance with Nasdaq Listing Rule 5635(c)(4).

						Shares						Weighted-Average Grant Date Fair Value Per Share
Unvested RSUs as of December 31, 2024						2,311,291						$	42.25
Granted						3,440,614						$	12.34
Released						(1,253,564)						$	40.06
Forfeited						(874,290)						$	22.81
Unvested RSUs as of December 31, 2025						3,624,051						$	18.59

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Tabular disclosure of the changes in outstanding nonvested restricted stock shares.

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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