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Equity - Additional Information (Details)
$ / shares in Units, $ in Millions
 1 Months Ended 12 Months Ended
Nov. 30, 2023
USD ($)
$ / shares
shares
Sep. 30, 2018
shares
Dec. 31, 2025
USD ($)
vote
$ / shares
shares
Dec. 31, 2024
USD ($)
$ / shares
shares
Dec. 31, 2023
USD ($)
$ / shares
shares
Dec. 31, 2019
shares
Sep. 17, 2025
USD ($)
Aug. 31, 2021
USD ($)
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Preferred stock, shares authorized (in shares) | shares     5,000,000 5,000,000        
Preferred stock par value (in dollars per share) | $ / shares     $ 0.001 $ 0.001        
Common stock, shares authorized (in shares) | shares     200,000,000 200,000,000        
Common stock, par value (in dollars per share) | $ / shares     $ 0.001 $ 0.001        
Number of votes per common stock share held | vote     1          
Warrant exercise price (in usd per share) | $ / shares         $ 0.001      
Proceeds from issuance of common stock and pre-funded warrants | $     $ 0.0 $ 0.0 $ 387.2      
Fees and expenses | $     $ 0.0 0.0 17.0      
Issuance of common stock for pre-funded warrants (in shares) | shares     3,422,186          
Share repurchase program, authorized amount | $             $ 100.0  
Share repurchases (Treasury Stock) (in shares) | shares     10,009,758          
Share repurchase program, average price (in dollars per share) | $ / shares     $ 9.09          
Share repurchase program, acquired, value net of commissions | $     $ 91.0          
Share repurchase program, commissions and excise tax | $     0.9          
Common stock issued, net of issuance costs | $         370.2      
Decrease in compensation expense | $     5.3          
Compensation expense | $     44.0 $ 88.2 $ 71.6      
Compensation expense not yet recognized | $     $ 30.4          
Inducement grants (in shares) | shares     255,611          
Weighted average grant date fair value of options granted (in usd per share) | $ / shares     $ 8.15 $ 27.35 $ 21.99      
Intrinsic value of options exercised | $     $ 0.0 $ 3.6 $ 1.4      
Weighted Average                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Compensation expense not yet recognized, period of recognition (in years)     1 year 6 months          
2018 Plan                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Common stock reserved for issuance (in shares) | shares   4,067,007            
Common stock, shares remained available for purchase (in shares) | shares     2,966,406          
Annual increase in reserved shares as percentage of outstanding common stock           4.00%    
2018 Plan | Maximum                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Common stock reserved for issuance (in shares) | shares   1,277,181            
2018 Plan | Minimum                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Annual increase in reserved shares of common stock (in shares) | shares           4,989,593    
ESPP                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Common stock reserved for issuance (in shares) | shares   311,850            
Common stock reserved for issuance represented as percentage on outstanding common stock   1.00%            
Common stock, shares remained available for purchase (in shares) | shares     3,577,025          
Common stock, shares issued (in shares) | shares     110,412 120,834 78,528      
ESPP | 2018 Plan                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Compensation expense | $     $ 0.5 $ 0.7 $ 0.8      
RSUs                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Number of inducement grants (in shares) | shares     170,365          
Granted (in dollars per share) | $ / shares     $ 12.34 $ 44.43 $ 32.27      
Total intrinsic value of RSUs released | $     $ 17.7 $ 13.2 $ 4.3      
Total fair value of RSUs vested | $     $ 44.3 $ 13.1 $ 6.9      
RSUs | 2018 Plan                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Granted (in dollars per share) | $ / shares     $ 12.34          
Pre-Funded Warrant                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Warrant exercise price (in usd per share) | $ / shares $ 0.001     $ 0.001        
Private Placement                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Proceeds from issuance of common stock and pre-funded warrants | $ $ 350.0              
Fees and expenses | $ 15.9              
At-the-Market Offering | Piper Sandler and Cantor | Equity Distribution Agreement                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Common stock aggregate offering price | $ $ 262.8              
Common stock issued, net of issuance costs (in shares) | shares     0 0        
Common Shares                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Issuance of common stock for pre-funded warrants (in shares) | shares     3,400,000          
Common stock issued, net of issuance costs (in shares) | shares         14,400,000      
Common Shares | Piper Sandler and Cantor | Equity Distribution Agreement                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Fees and expenses | $         $ 1.1      
Common stock aggregate offering price | $               $ 300.0
Common stock issued, net of issuance costs (in shares) | shares         1,449,275      
Common stock issued, net of issuance costs | $         $ 37.2      
Common Shares | Private Placement                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Number of shares issued in transaction (in shares) | shares 12,963,542              
Sale of stock, price (in usd per share) | $ / shares $ 21.36              
Common Shares | Private Placement | Pre-Funded Warrant                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Sale of stock, price (in usd per share) | $ / shares $ 21.359              
Warrants to be purchased (in shares) | shares 3,422,380