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Commitments and Contingencies (Details) $ in Thousands		1 Months Ended	12 Months Ended
	Jul. 05, 2013 USD ($) product	Jun. 30, 2024 USD ($)	Dec. 31, 2025 USD ($)	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)	Jun. 30, 2025 USD ($)
Commitments And Contingencies [Line Items]
Loss contingency			$ 0	$ 5,000	$ 15,200
Yale University
Commitments And Contingencies [Line Items]
Royalty payment			$ 700	$ 0	$ 300
Yale University | Maximum
Commitments And Contingencies [Line Items]
Royalty payment	$ 500
Yale University | Minimum
Commitments And Contingencies [Line Items]
Annual payment for license	$ 100
Number of licensed products | product	2
Royalty payment	$ 200
Yale University | Upfront Payment For Amended License Agreement And Novartis License And Asset Agreements
Commitments And Contingencies [Line Items]
Payments for collaboration		$ 14,950
Yale University | Milestone Payment On First Anniversary Of Signing
Commitments And Contingencies [Line Items]
Milestone payment the Company will make						$ 5,000
Yale University | Milestone Payment Upon Approval Of First And Second Royalty Products | Maximum
Commitments And Contingencies [Line Items]
Milestone payment the Company will make						$ 15,000
Yale University | Success-Based Milestone Payments | License, First Licensed Product
Commitments And Contingencies [Line Items]
Required milestone payments	3,000
Yale University | Success-Based Milestone Payments | License, Second Licensed Product
Commitments And Contingencies [Line Items]
Required milestone payments	$ 1,500

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+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 450
-SubTopic 20
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-Section 50
-Paragraph 1
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-URI https://asc.fasb.org/1943274/2147483076/450-20-50-1

Reference 2: http://www.xbrl.org/2003/role/recommendedDisclosureRef
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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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-Topic 230
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