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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2018
Income Tax Disclosure [Abstract] |
Schedule of Components of Loss Before Income Taxes | The components of the Company’s loss before income taxes are as follows (in thousands):
| Year Ended December 31,
| 2018 |  | 2017
Domestic | (16,835 | ) |  | (22,717 | )
Foreign | (618 | ) |  | (322 | )
Loss before income taxes | (17,453 | ) |  | (23,039 | )
Schedule of Components of Income Tax Expense | The components of income tax expense are as follows (in thousands):
| Year Ended December 31,
| 2018 |  | 2017
Current tax expense: |  |  |
Federal | $ | — |  |  | $ | — |
State | — |  |  | — |
Foreign | — |  |  | — |
Total current tax expense | — |  |  | — |
Deferred tax expense: |  |  |
Federal | 3,555 |  |  | (9,574 | )
State | 822 |  |  | 2,061 |
Foreign | 200 |  |  | — |
Total deferred tax expense | 4,577 |  |  | (7,513 | )
Change in deferred tax valuation allowance | (4,577 | ) |  | 7,513 |
Net deferred tax expense | — |  |  | — |
Provision for income taxes | $ | — |  |  | $ | — |
Schedule of Effective Income Tax Rate Reconciliation | Income tax expense differs from the amount computed by applying the statutory federal income tax rate due to the following:
| Year Ended December 31,
| 2018 |  | 2017
Tax at statutory federal rate | (21.0 | )% |  | (34.0 | )%
State tax, net of federal benefit | (5.3 | )% |  | (4.3 | )%
Measurement of deferred taxes as a result of tax reform | — | % |  | 68.7 | %
Tax credits | (0.7 | )% |  | (0.3 | )%
Change in deferred tax valuation allowance | 26.2 | % |  | (32.6 | )%
Other | 0.8 | % |  | 2.5 | %
Total income tax expense | — | % |  | — | %
Schedule of Deferred Tax Assets | The tax effects of temporary differences and carryforwards that give rise to significant portions of the deferred tax assets are presented below (in thousands):
| December 31,
| 2018 |  | 2017
Net operating loss carryforwards | $ | 35,067 |  |  | $ | 32,210 |
Research and development credits | 2,255 |  |  | 2,070 |
Depreciation and amortization | 132 |  |  | 179 |
Accruals and reserves | 2,958 |  |  | 1,376 |
| 40,412 |  |  | 35,835 |
Less: Valuation allowance | (40,412 | ) |  | (35,835 | )
Total deferred tax asset | $ | — |  |  | $ | — |
Summary of Changes in Valuation Allowance | The following table summarizes changes in the valuation allowance for the year ended December 31, 2018 and 2017 (in thousands):
| December 31,
| 2018 |  | 2017
Beginning balance | $ | 35,835 |  |  | $ | 43,348 |
Additions during the period | 4,577 |  |  | — |
Deductions during the period | — |  |  | (7,513 | )
Ending balance | $ | 40,412 |  |  | $ | 35,835 |
Schedule of Uncertain Income Tax Positions | The changes in the Company’s uncertain income tax positions for the years ended December 31, 2018 and 2017 consisted of the following (in thousands):
Beginning balance as of January 1, 2017 | $ | 950 |
Increases in balances related to tax positions taken during 2017 | 43 |
Ending balance as of December 31, 2017 | 993 |
Increases in balances related to tax positions taken during 2018 | 91 |
Ending balance as of December 31, 2018 | $ | 1,084 |

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- Definition Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 9 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32639-109319 + Details
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