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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2019 | Jun. 30, 2018
Cash flows from operating activities |  |
Net loss | $ (17,999) | $ (7,348)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation | 3,685 | 754
Depreciation and amortization | 395 | 356
Accretion on marketable securities | (940) | 0
Amortization of debt discount | 130 | 130
Change in fair value of redeemable convertible preferred stock warrants | 0 | 224
Loss on sale and disposal of property and equipment | 98 | 48
Changes in operating assets and liabilities: |  |
Accounts receivable | (916) | 194
Inventory | (1,092) | (320)
Prepaid expenses and other assets | 102 | 237
Accounts payable | 338 | (462)
Accrued liabilities and other | 725 | 514
Net cash used in operating activities | (15,474) | (5,673)
Cash flows from investing activities |  |
Maturities of marketable securities | 83,600 | 0
Purchases of marketable securities | (82,516) | 0
Purchases of property and equipment | (893) | (715)
Net cash provided by (used in) investing activities | 191 | (715)
Cash flows from financing activities |  |
Proceeds from the exercise of stock options | 567 | 208
Proceeds from issuance of common stock under employee stock purchase plan | 1,263 | 0
Payments of public offering costs | (167) | 0
Net cash provided by financing activities | 1,663 | 208
Effect of exchange rate changes on cash and cash equivalents | (4) | 5
Net decrease in cash and cash equivalents | (13,624) | (6,175)
Cash and cash equivalents at |  |
Beginning of period | 25,120 | 22,408
End of period | 11,496 | 16,233
Supplemental disclosure of non-cash information |  |
Vesting of early exercised stock options | 122 | 28
Purchases of property and equipment included in accounts payable and accrued liabilities | $ 57 | $ 97

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- Definition The sum of the periodic adjustments of the differences between securities' face values and purchase prices that are charged against earnings. This is called accretion if the security was purchased at a discount and amortization if it was purchased at premium. As a noncash item, this element is an adjustment to net income when calculating cash provided by or used in operations using the indirect method. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=109223946&loc=d3e3602-108585 + Details
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