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Condensed Quarterly Financial Data (unaudited) (Details) (USD $) In Thousands, except Per Share data, unless otherwise specified | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2014 | Sep. 30, 2014 | Jun. 30, 2014 | Mar. 31, 2014 | Dec. 31, 2013 | Sep. 30, 2013 | Jun. 30, 2013 | Mar. 31, 2013 | Dec. 31, 2014 | Dec. 31, 2013 | Dec. 31, 2012
Condensed Quarterly Financial Data (unaudited) |  |  |  |  |  |  |  |  |  |  |
Total revenue | $ 5,664 xncr_CollaborationsLicensesAndMilestonesRevenue | $ 848 xncr_CollaborationsLicensesAndMilestonesRevenue | $ 824 xncr_CollaborationsLicensesAndMilestonesRevenue | $ 2,184 xncr_CollaborationsLicensesAndMilestonesRevenue | $ 1,745 xncr_CollaborationsLicensesAndMilestonesRevenue | $ 3,161 xncr_CollaborationsLicensesAndMilestonesRevenue | $ 3,921 xncr_CollaborationsLicensesAndMilestonesRevenue | $ 1,345 xncr_CollaborationsLicensesAndMilestonesRevenue | $ 9,520 xncr_CollaborationsLicensesAndMilestonesRevenue | $ 10,172 xncr_CollaborationsLicensesAndMilestonesRevenue | $ 9,524 xncr_CollaborationsLicensesAndMilestonesRevenue
Loss from operations | (1,350)us-gaap_OperatingIncomeLoss | (6,287)us-gaap_OperatingIncomeLoss | (5,053)us-gaap_OperatingIncomeLoss | (3,767)us-gaap_OperatingIncomeLoss | (3,710)us-gaap_OperatingIncomeLoss | (1,843)us-gaap_OperatingIncomeLoss | (1,006)us-gaap_OperatingIncomeLoss | (3,961)us-gaap_OperatingIncomeLoss | (16,457)us-gaap_OperatingIncomeLoss | (10,520)us-gaap_OperatingIncomeLoss | (6,230)us-gaap_OperatingIncomeLoss
Net loss | $ (1,349)xncr_NetProfitLoss | $ (6,278)xncr_NetProfitLoss | $ (5,044)xncr_NetProfitLoss | $ (3,751)xncr_NetProfitLoss | $ (3,703)xncr_NetProfitLoss | $ (1,835)xncr_NetProfitLoss | $ (50,109)xncr_NetProfitLoss | $ (4,612)xncr_NetProfitLoss | $ (16,422)xncr_NetProfitLoss | $ (60,259)xncr_NetProfitLoss | $ (8,594)xncr_NetProfitLoss
Basic (in dollars per share) | $ (0.04)us-gaap_EarningsPerShareBasic | $ (0.20)us-gaap_EarningsPerShareBasic | $ (0.16)us-gaap_EarningsPerShareBasic | $ (0.12)us-gaap_EarningsPerShareBasic | $ (0.37)us-gaap_EarningsPerShareBasic | $ (57.87)us-gaap_EarningsPerShareBasic | $ 1,341.67 us-gaap_EarningsPerShareBasic | $ (63.78)us-gaap_EarningsPerShareBasic | $ (0.52)us-gaap_EarningsPerShareBasic | $ 34.18 us-gaap_EarningsPerShareBasic | $ (118.86)us-gaap_EarningsPerShareBasic
Diluted (in dollars per share) | $ (0.04)us-gaap_EarningsPerShareDiluted | $ (0.20)us-gaap_EarningsPerShareDiluted | $ (0.16)us-gaap_EarningsPerShareDiluted | $ (0.12)us-gaap_EarningsPerShareDiluted | $ (0.37)us-gaap_EarningsPerShareDiluted | $ (57.87)us-gaap_EarningsPerShareDiluted | $ (3.88)us-gaap_EarningsPerShareDiluted | $ (63.78)us-gaap_EarningsPerShareDiluted | $ (0.52)us-gaap_EarningsPerShareDiluted | $ (3.85)us-gaap_EarningsPerShareDiluted | $ (118.86)us-gaap_EarningsPerShareDiluted

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