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Income Taxes (Tables)

12 Months Ended

Dec. 31, 2014

Income Taxes

Reconciliation of the federal statutory income tax rate to our effective income tax rate

		Year Ended
		December 31,
		2014			2013			2012
Federal statutory income tax rate		$	(5,583)		$	(20,488)		$	(2,922)
Loss on settlement of notes			—			18,884			—
Non-deductible research and development credit			435			—			336
Stock based compensation			478			—			—
Other			2			4			12
Net change in valuation allowance			4,668			1,600			2,574
Net effective tax rate		$	—		$	—		$	—

Schedule of tax effect of temporary differences that give rise to a significant portion of the deferred tax assets and liabilities

		2014			2013
Deferred income tax assets
Net operating loss carryforwards		$	47,401		$	58,286
Research credits			12,789			24,276
Depreciation			790			849
Stock-based compensation			—			52
Accrued compensation			373			137
Deferred revenue			1,836			3,899
Gross deferred income tax assets			63,189			87,499
Valuation allowance			(59,602)			(84,045)
Net deferred income tax assets			3,587			3,454
Deferred income tax liabilities
Patent costs			(3,199)			(2,929)
Licensing costs			(317)			(406)
Capitalized legal costs			(71)			(119)
Gross deferred income tax liabilities			(3,587)			(3,454)
Net deferred income tax asset/(liability)		$	—		$	—

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- Definition

Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 740

-SubTopic 10

-Section 50

-Paragraph 2

-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32537-109319

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- Definition

Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 740

-SubTopic 10

-Section 50

-Paragraph 12

-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32687-109319

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