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Summary of Significant Accounting Policies (Details 2) (USD $)
 3 Months Ended 12 Months Ended 0 Months Ended 1 Months Ended
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2014
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Dec. 31, 2013
Dec. 31, 2012
Sep. 23, 2013
Jun. 26, 2013
Sep. 30, 2013
Jun. 30, 2013
Outstanding potentially dilutive securities have been excluded from the computations of diluted net loss per common share                              
Anti-dilutive securities (in shares)                 2,852,000us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount 1,794,000us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount 16,293,000us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount        
Deemed dividend (in dollars)                   $ (3,429,000)xncr_ConvertiblePreferredStockDeemedDividend          
Basic numerator:                              
Net loss (1,349,000)xncr_NetProfitLoss (6,278,000)xncr_NetProfitLoss (5,044,000)xncr_NetProfitLoss (3,751,000)xncr_NetProfitLoss (3,703,000)xncr_NetProfitLoss (1,835,000)xncr_NetProfitLoss (50,109,000)xncr_NetProfitLoss (4,612,000)xncr_NetProfitLoss (16,422,000)xncr_NetProfitLoss (60,259,000)xncr_NetProfitLoss (8,594,000)xncr_NetProfitLoss        
Deemed contribution (distribution) on exchange of preferred stock                   144,765,000xncr_DeemedContributionOnExchangeOfPreferredStock          
Net income (loss) attributable to common stockholders for basic net income (loss) per share                 (16,422,000)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic 84,506,000us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic (8,594,000)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic        
Denominator:                              
Weighted average common shares outstanding                 31,390,631us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 2,472,581us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 72,302us-gaap_WeightedAverageNumberOfSharesOutstandingBasic        
Basic net income (loss) per common share (in dollars per share) $ (0.04)us-gaap_EarningsPerShareBasic $ (0.20)us-gaap_EarningsPerShareBasic $ (0.16)us-gaap_EarningsPerShareBasic $ (0.12)us-gaap_EarningsPerShareBasic $ (0.37)us-gaap_EarningsPerShareBasic $ (57.87)us-gaap_EarningsPerShareBasic $ 1,341.67us-gaap_EarningsPerShareBasic $ (63.78)us-gaap_EarningsPerShareBasic $ (0.52)us-gaap_EarningsPerShareBasic $ 34.18us-gaap_EarningsPerShareBasic $ (118.86)us-gaap_EarningsPerShareBasic        
Diluted numerator:                              
Net income (loss) attributable to common stockholders for basic net income (loss) per share                 (16,422,000)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic 84,506,000us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic (8,594,000)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic        
Deemed contribution                   144,765,000xncr_DeemedContributionOnExchangeOfPreferredStockToComputeDilutedIncomeLossPerShare          
Net loss attributable to common stockholders for diluted net loss per share                 (16,422,000)us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted (60,259,000)us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted (8,594,000)us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted        
Denominator                              
Weighted average common shares outstanding                 31,390,631us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 2,472,581us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 72,302us-gaap_WeightedAverageNumberOfSharesOutstandingBasic        
Dilutive effect of conversion of convertible preferred stock                   13,173,208us-gaap_IncrementalCommonSharesAttributableToConversionOfPreferredStock          
Weighted Average Number of Shares Outstanding, Diluted                 31,390,631us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 15,645,789us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 72,302us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding        
Diluted net loss per common share $ (0.04)us-gaap_EarningsPerShareDiluted $ (0.20)us-gaap_EarningsPerShareDiluted $ (0.16)us-gaap_EarningsPerShareDiluted $ (0.12)us-gaap_EarningsPerShareDiluted $ (0.37)us-gaap_EarningsPerShareDiluted $ (57.87)us-gaap_EarningsPerShareDiluted $ (3.88)us-gaap_EarningsPerShareDiluted $ (63.78)us-gaap_EarningsPerShareDiluted $ (0.52)us-gaap_EarningsPerShareDiluted $ (3.85)us-gaap_EarningsPerShareDiluted $ (118.86)us-gaap_EarningsPerShareDiluted        
Segment Reporting [Abstract]                              
Number of Operating Segments                 1us-gaap_NumberOfOperatingSegments            
Stock-Based Compensation                              
Stock-based compensation expense                 1,861,000us-gaap_AllocatedShareBasedCompensationExpense 198,000us-gaap_AllocatedShareBasedCompensationExpense 29,000us-gaap_AllocatedShareBasedCompensationExpense        
Deferred Revenue                              
Deferred revenue                 4,600,000us-gaap_DeferredRevenueRevenueRecognized 9,700,000us-gaap_DeferredRevenueRevenueRecognized          
Number of primary technology groups                 4xncr_NumberOfPrimaryTechnologyGroupsUnderPatents            
Convertible preferred stock                              
Outstanding potentially dilutive securities have been excluded from the computations of diluted net loss per common share                              
Anti-dilutive securities (in shares)                     12,188,000us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_ConvertiblePreferredStockMember		        
Convertible Promissory Notes                              
Outstanding potentially dilutive securities have been excluded from the computations of diluted net loss per common share                              
Anti-dilutive securities (in shares)                     2,800,000us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_ConvertibleNotesPayableMember		        
Employee stock options                              
Outstanding potentially dilutive securities have been excluded from the computations of diluted net loss per common share                              
Anti-dilutive securities (in shares)                 2,827,000us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_EmployeeStockOptionMember		 1,794,000us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_EmployeeStockOptionMember		 1,305,000us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_EmployeeStockOptionMember		        
Employee Stock Purchase Plan                              
Outstanding potentially dilutive securities have been excluded from the computations of diluted net loss per common share                              
Anti-dilutive securities (in shares)                 25,000us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_EmployeeStockMember		            
Stock-Based Compensation                              
Stock-based compensation expense                 172,000us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_EmployeeStockMember		            
Series A-1 Convertible Preferred Stock                              
Outstanding potentially dilutive securities have been excluded from the computations of diluted net loss per common share                              
Deemed dividend (in dollars)                       2,300,000xncr_ConvertiblePreferredStockDeemedDividend
/ us-gaap_StatementClassOfStockAxis
= xncr_SeriesA1ConvertiblePreferredStockMember		 1,000,000xncr_ConvertiblePreferredStockDeemedDividend
/ us-gaap_StatementClassOfStockAxis
= xncr_SeriesA1ConvertiblePreferredStockMember		   1,000,000xncr_ConvertiblePreferredStockDeemedDividend
/ us-gaap_StatementClassOfStockAxis
= xncr_SeriesA1ConvertiblePreferredStockMember
Deemed contribution                           2,300,000xncr_DeemedContributionOnExchangeOfPreferredStockBeforeDeductingDeemedDividend
/ us-gaap_StatementClassOfStockAxis
= xncr_SeriesA1ConvertiblePreferredStockMember		  
Diluted numerator:                              
Deemed contribution                   $ 148,100,000xncr_DeemedContributionOnExchangeOfPreferredStockToComputeDilutedIncomeLossPerShare
/ us-gaap_StatementClassOfStockAxis
= xncr_SeriesA1ConvertiblePreferredStockMember