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Property and Equipment (Details) (USD $)	12 Months Ended
	Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012
Property and equipment
Property and equipment, gross	$ 7,453,000us-gaap_PropertyPlantAndEquipmentGross	$ 6,684,000us-gaap_PropertyPlantAndEquipmentGross
Less accumulated depreciation and amortization	(6,554,000)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment	(6,377,000)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
Property, Plant and Equipment, Net	899,000us-gaap_PropertyPlantAndEquipmentNet	307,000us-gaap_PropertyPlantAndEquipmentNet
Depreciation expense	188,000us-gaap_Depreciation	113,000us-gaap_Depreciation	154,000us-gaap_Depreciation
Computers, software and equipment
Property and equipment
Property and equipment, gross	4,270,000us-gaap_PropertyPlantAndEquipmentGross / us-gaap_PropertyPlantAndEquipmentByTypeAxis = xncr_ComputersSoftwareAndEquipmentMember	3,514,000us-gaap_PropertyPlantAndEquipmentGross / us-gaap_PropertyPlantAndEquipmentByTypeAxis = xncr_ComputersSoftwareAndEquipmentMember
Furniture and fixtures
Property and equipment
Property and equipment, gross	97,000us-gaap_PropertyPlantAndEquipmentGross / us-gaap_PropertyPlantAndEquipmentByTypeAxis = us-gaap_FurnitureAndFixturesMember	89,000us-gaap_PropertyPlantAndEquipmentGross / us-gaap_PropertyPlantAndEquipmentByTypeAxis = us-gaap_FurnitureAndFixturesMember
Leasehold and tenant improvements
Property and equipment
Property and equipment, gross	3,086,000us-gaap_PropertyPlantAndEquipmentGross / us-gaap_PropertyPlantAndEquipmentByTypeAxis = us-gaap_LeaseholdsAndLeaseholdImprovementsMember	3,081,000us-gaap_PropertyPlantAndEquipmentGross / us-gaap_PropertyPlantAndEquipmentByTypeAxis = us-gaap_LeaseholdsAndLeaseholdImprovementsMember
Capital lease
Property and equipment
Property and equipment, gross	22,000us-gaap_PropertyPlantAndEquipmentGross / us-gaap_PropertyPlantAndEquipmentByTypeAxis = us-gaap_AssetsHeldUnderCapitalLeasesMember	22,000us-gaap_PropertyPlantAndEquipmentGross / us-gaap_PropertyPlantAndEquipmentByTypeAxis = us-gaap_AssetsHeldUnderCapitalLeasesMember
Less accumulated depreciation and amortization	(20,000)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment / us-gaap_PropertyPlantAndEquipmentByTypeAxis = us-gaap_AssetsHeldUnderCapitalLeasesMember	(12,900)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment / us-gaap_PropertyPlantAndEquipmentByTypeAxis = us-gaap_AssetsHeldUnderCapitalLeasesMember
Capital lease entered for computer equipment			$ 22,000us-gaap_PropertyPlantAndEquipmentAdditions / us-gaap_PropertyPlantAndEquipmentByTypeAxis = us-gaap_AssetsHeldUnderCapitalLeasesMember

X

- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 360

-SubTopic 10

-Section 50

-Paragraph 1

-Subparagraph (c)

-URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229



Reference 2: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 210

-SubTopic 10

-Section S99

-Paragraph 1

-Subparagraph (SX 210.5-02.14)

-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682



Reference 3: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Regulation S-X (SX)

-Number 210

-Section 02

-Paragraph 14

-Article 5

+ Details

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X

- Definition

The amount of expense recognized in the current period that reflects the allocation of the cost of tangible assets over the assets' useful lives. Includes production and non-production related depreciation.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 230

-SubTopic 10

-Section 45

-Paragraph 28

-Subparagraph (b)

-URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585

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X

- Definition

Amount of acquisition of long-lived, physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

+ References

No definition available.

+ Details

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X

- Definition

Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 360

-SubTopic 10

-Section 50

-Paragraph 1

-Subparagraph (b)

-URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229



Reference 2: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 210

-SubTopic 10

-Section S99

-Paragraph 1

-Subparagraph (SX 210.5-02.13)

-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

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- Definition

Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 360

-SubTopic 10

-Section 50

-Paragraph 1

-URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229



Reference 2: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 210

-SubTopic 10

-Section S99

-Paragraph 1

-Subparagraph (SX 210.5-02.13)

-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682



Reference 3: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Regulation S-X (SX)

-Number 210

-Section 02

-Paragraph 13

-Subparagraph a

-Article 5



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-Publisher SEC

-Name Regulation S-X (SX)

-Number 210

-Section 03

-Paragraph 8

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