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Stock-Based Compensation (Details 2) (Stock options, USD $)
12 Months Ended 13 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2014
Stock option activity, Number of Shares        
Balance at the beginning of the period (in shares) 1,794,214us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber 1,304,848us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber    
Options granted (in shares) 1,049,521us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross 517,062us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross    
Options canceled (in shares)   (5,305)us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod    
Options forfeited (in shares) (1,000)us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod      
Options exercised (in shares) (15,941)us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised (22,391)us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised 0us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised  
Balance at the end of the period (in shares) 2,826,794us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber 1,794,214us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber 1,304,848us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber 2,826,794us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
Options vested and expected to vest (in shares) 2,531,221us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber     2,531,221us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber
Exercisable (in shares) 1,393,729us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber 1,203,885us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber 1,094,573us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber 1,393,729us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
Weighted Average Exercise Price (Per Share)        
Balance at the beginning of the period (in dollars per share) $ 1.66us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice $ 0.59us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice    
Options granted (in dollars per share) $ 10.99us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice $ 4.29us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice    
Options canceled (in dollars per share)   $ 0.59us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice    
Options forfeited (in dollars per share) $ 10.31us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice      
Options exercised (in dollars per share) $ 0.59us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice $ 0.59us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice    
Balance at the end of the period (in dollars per share) $ 5.12us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice $ 1.66us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice $ 0.59us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice 5.12us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
Options vested and expected to vest (in dollars per share) $ 4.72us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice     4.72us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice
Exercisable (in dollars per share) $ 1.01us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice $ 0.59us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice $ 0.59us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice 1.01us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
Additional information        
Weighted-Average Remaining Contractual Term, Balance outstanding 6 years 5 months 5 days 5 years 8 months 19 days 7 years 9 months 15 days  
Weighted-Average Remaining Contractual Term, Options vested and expected to vest 6 years 1 month 13 days      
Weighted-Average Remaining Contractual Term, Exercisable 3 years 8 months 5 days      
Aggregate Intrinsic Value, Balance outstanding $ 30,863,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue $ 13,429,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue   30,863,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
Aggregate Intrinsic Value, Options vested and expected to vest 28,642,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue     28,642,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue
Aggregate Intrinsic Value, Exercisable 20,949,000us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1     20,949,000us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
Intrinsic value of options exercised $ 155,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue $ 191,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue    
The 2013 Plan        
Stock option activity, Number of Shares        
Options granted (in shares)       1,063,500us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
/ us-gaap_AwardTypeAxis
= xncr_EmployeeAndNonEmployeeStockOptionMember
/ us-gaap_PlanNameAxis
= xncr_EquityIncentivePlan2013Member