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Stock-Based Compensation (Details 3) (USD $)	12 Months Ended
	Dec. 31, 2014
Stock options outstanding and exercisable by exercise price
Stock Options Outstanding, Number of Shares	2,826,794us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfOutstandingOptions
Stock Options Outstanding, Remaining Contractual Term	6 years 5 months 5 days
Stock Options Outstanding, Weighted-Average Exercise Price (in dollars per share)	$ 5.12us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1
Stock Options Exercisable, Number of Shares	1,393,729us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfExercisableOptions
Stock Options Exercisable, Weighted-Average Exercise Price (in dollars per share)	$ 1.01us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1
$0.59 - $4.25
Stock options outstanding and exercisable by exercise price
Range of Exercise Prices, lower limit (in dollars per share)	$ 0.59us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeOneMember
Range of Exercise Prices, upper limit (in dollars per share)	$ 4.25us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeOneMember
Stock Options Outstanding, Number of Shares	1,763,294us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfOutstandingOptions / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeOneMember
Stock Options Outstanding, Remaining Contractual Term	4 years 8 months 16 days
Stock Options Outstanding, Weighted-Average Exercise Price (in dollars per share)	$ 1.63us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1 / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeOneMember
Stock Options Exercisable, Number of Shares	1,388,779us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfExercisableOptions / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeOneMember
Stock Options Exercisable, Weighted-Average Exercise Price (in dollars per share)	$ 0.99us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1 / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeOneMember
$4.25 - $8.56
Stock options outstanding and exercisable by exercise price
Range of Exercise Prices, lower limit (in dollars per share)	$ 4.25us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeTwoMember
Range of Exercise Prices, upper limit (in dollars per share)	$ 8.56us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeTwoMember
Stock Options Outstanding, Number of Shares	55,000us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfOutstandingOptions / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeTwoMember
Stock Options Outstanding, Remaining Contractual Term	9 years 3 months 11 days
Stock Options Outstanding, Weighted-Average Exercise Price (in dollars per share)	$ 7.73us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1 / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeTwoMember
Stock Options Exercisable, Number of Shares	4,950us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfExercisableOptions / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeTwoMember
Stock Options Exercisable, Weighted-Average Exercise Price (in dollars per share)	$ 5.50us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1 / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeTwoMember
$9.26 – 16.52
Stock options outstanding and exercisable by exercise price
Range of Exercise Prices, lower limit (in dollars per share)	$ 9.26us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeThreeMember
Range of Exercise Prices, upper limit (in dollars per share)	$ 16.52us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeThreeMember
Stock Options Outstanding, Number of Shares	1,008,500us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfOutstandingOptions / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeThreeMember
Stock Options Outstanding, Remaining Contractual Term	9 years 3 months 11 days
Stock Options Outstanding, Weighted-Average Exercise Price (in dollars per share)	$ 11.10us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageExercisePriceBeginningBalance1 / us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis = xncr_SharesAuthorizedUnderStockOptionPlansExercisePriceRangeThreeMember

X

- Definition

Weighted average exercise price as of the balance sheet date for those equity-based payment arrangements exercisable and outstanding.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 718

-SubTopic 10

-Section 50

-Paragraph 2

-Subparagraph (c)(1)(iii)

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- Definition

The floor of a customized range of exercise prices for purposes of disclosing shares potentially issuable under outstanding stock option awards on all stock option plans and other required information pertaining to awards in the customized range.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 718

-SubTopic 10

-Section 50

-Paragraph 2

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- Definition

The number of shares reserved for issuance pertaining to the outstanding exercisable stock options as of the balance sheet date in the customized range of exercise prices for which the market and performance vesting condition has been satisfied.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 718

-SubTopic 10

-Section 50

-Paragraph 2

-Subparagraph (c)(iii)

-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

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+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 718

-SubTopic 10

-Section 50

-Paragraph 2

-Subparagraph (c)(1)(i)-(ii)

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- Definition

The weighted average price as of the balance sheet date at which grantees could acquire the underlying shares with respect to all outstanding stock options which are in the customized range of exercise prices.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 718

-SubTopic 10

-Section 50

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- Definition

Weighted average remaining contractual term of outstanding stock options, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 718

-SubTopic 10

-Section 50

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The ceiling of a customized range of exercise prices for purposes of disclosing shares potentially issuable under outstanding stock option awards on all stock option plans and other required information pertaining to awards in the customized range.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 718

-SubTopic 10

-Section 50

-Paragraph 2

-Subparagraph (g)

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