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Condensed Quarterly Financial Data (unaudited) (Details) (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended								12 Months Ended
	Dec. 31, 2014	Sep. 30, 2014	Jun. 30, 2014	Mar. 31, 2014	Dec. 31, 2013	Sep. 30, 2013	Jun. 30, 2013	Mar. 31, 2013	Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012
Condensed Quarterly Financial Data (unaudited)
Total revenue	$ 5,664xncr_CollaborationsLicensesAndMilestonesRevenue	$ 848xncr_CollaborationsLicensesAndMilestonesRevenue	$ 824xncr_CollaborationsLicensesAndMilestonesRevenue	$ 2,184xncr_CollaborationsLicensesAndMilestonesRevenue	$ 1,745xncr_CollaborationsLicensesAndMilestonesRevenue	$ 3,161xncr_CollaborationsLicensesAndMilestonesRevenue	$ 3,921xncr_CollaborationsLicensesAndMilestonesRevenue	$ 1,345xncr_CollaborationsLicensesAndMilestonesRevenue	$ 9,520xncr_CollaborationsLicensesAndMilestonesRevenue	$ 10,172xncr_CollaborationsLicensesAndMilestonesRevenue	$ 9,524xncr_CollaborationsLicensesAndMilestonesRevenue
Loss from operations	(1,350)us-gaap_OperatingIncomeLoss	(6,287)us-gaap_OperatingIncomeLoss	(5,053)us-gaap_OperatingIncomeLoss	(3,767)us-gaap_OperatingIncomeLoss	(3,710)us-gaap_OperatingIncomeLoss	(1,843)us-gaap_OperatingIncomeLoss	(1,006)us-gaap_OperatingIncomeLoss	(3,961)us-gaap_OperatingIncomeLoss	(16,457)us-gaap_OperatingIncomeLoss	(10,520)us-gaap_OperatingIncomeLoss	(6,230)us-gaap_OperatingIncomeLoss
Net loss	$ (1,349)xncr_NetProfitLoss	$ (6,278)xncr_NetProfitLoss	$ (5,044)xncr_NetProfitLoss	$ (3,751)xncr_NetProfitLoss	$ (3,703)xncr_NetProfitLoss	$ (1,835)xncr_NetProfitLoss	$ (50,109)xncr_NetProfitLoss	$ (4,612)xncr_NetProfitLoss	$ (16,422)xncr_NetProfitLoss	$ (60,259)xncr_NetProfitLoss	$ (8,594)xncr_NetProfitLoss
Basic (in dollars per share)	$ (0.04)us-gaap_EarningsPerShareBasic	$ (0.20)us-gaap_EarningsPerShareBasic	$ (0.16)us-gaap_EarningsPerShareBasic	$ (0.12)us-gaap_EarningsPerShareBasic	$ (0.37)us-gaap_EarningsPerShareBasic	$ (57.87)us-gaap_EarningsPerShareBasic	$ 1,341.67us-gaap_EarningsPerShareBasic	$ (63.78)us-gaap_EarningsPerShareBasic	$ (0.52)us-gaap_EarningsPerShareBasic	$ 34.18us-gaap_EarningsPerShareBasic	$ (118.86)us-gaap_EarningsPerShareBasic
Diluted (in dollars per share)	$ (0.04)us-gaap_EarningsPerShareDiluted	$ (0.20)us-gaap_EarningsPerShareDiluted	$ (0.16)us-gaap_EarningsPerShareDiluted	$ (0.12)us-gaap_EarningsPerShareDiluted	$ (0.37)us-gaap_EarningsPerShareDiluted	$ (57.87)us-gaap_EarningsPerShareDiluted	$ (3.88)us-gaap_EarningsPerShareDiluted	$ (63.78)us-gaap_EarningsPerShareDiluted	$ (0.52)us-gaap_EarningsPerShareDiluted	$ (3.85)us-gaap_EarningsPerShareDiluted	$ (118.86)us-gaap_EarningsPerShareDiluted

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