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Summary of Significant Accounting Policies - Net Loss Per Share (Details) - USD ($) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2017 | Sep. 30, 2017 | Jun. 30, 2017 | Mar. 31, 2017 | Dec. 31, 2016 | Sep. 30, 2016 | Jun. 30, 2016 | Mar. 31, 2016 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Net Income (Loss) Per Share |  |  |  |  |  |  |  |  |  |  |
Anti-dilutive securities (in shares) |  |  |  |  |  |  |  |  | 1,291,000 |  | 1,356,000
Stock-Based Compensation |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation expense |  |  |  |  |  |  |  |  | $ 13,651,000 | $ 7,848,000 | $ 4,869,000
Basic numerator: |  |  |  |  |  |  |  |  |  |  |
Net income (loss) attributable to common stockholders for basic net income (loss) per share |  |  |  |  |  |  |  |  | $ (48,925,000) | $ 23,625,000 | $ (17,592,000)
Denominator: |  |  |  |  |  |  |  |  |  |  |
Weighted average common shares outstanding, basic |  |  |  |  |  |  |  |  | 46,817,756 | 41,267,329 | 39,015,131
Net income (loss) per common share, basic (in dollars per share) | $ (0.25) | $ (0.33) | $ (0.15) | $ (0.31) | $ (0.21) | $ (0.20) | $ 1.16 | $ (0.16) | $ (1.05) | $ 0.57 | $ (0.45)
Diluted numerator: |  |  |  |  |  |  |  |  |  |  |
Net income (loss) attributable to common stockholders for diluted net income (loss) per share |  |  |  |  |  |  |  |  | $ (48,925,000) | $ 23,625,000 | $ (17,592,000)
Denominator |  |  |  |  |  |  |  |  |  |  |
Weighted average common shares outstanding, basic |  |  |  |  |  |  |  |  | 46,817,756 | 41,267,329 | 39,015,131
Dilutive effect of conversion of convertible preferred stock |  |  |  |  |  |  |  |  |  | 1,121,538 |
Weighted average common shares outstanding, diluted |  |  |  |  |  |  |  |  | 46,817,756 | 42,388,867 | 39,015,131
Net income (loss) per common share, diluted (in dollars per share) | $ (0.25) | $ (0.33) | $ (0.15) | $ (0.31) | $ (0.21) | $ (0.20) | $ 1.13 | $ (0.16) | $ (1.05) | $ 0.56 | $ (0.45)
Employee stock options |  |  |  |  |  |  |  |  |  |  |
Net Income (Loss) Per Share |  |  |  |  |  |  |  |  |  |  |
Anti-dilutive securities (in shares) |  |  |  |  |  |  |  |  | 1,291,000 |  | 1,281,000
Employee Stock Purchase Plan |  |  |  |  |  |  |  |  |  |  |
Net Income (Loss) Per Share |  |  |  |  |  |  |  |  |  |  |
Anti-dilutive securities (in shares) |  |  |  |  |  |  |  |  |  |  | 75,000
Stock-Based Compensation |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation expense |  |  |  |  |  |  |  |  | $ 498,000 | $ 378,000 |

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