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Summary of Significant Accounting Policies - Net Loss Per Share (Details) - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Net Income (Loss) Per Share                      
Anti-dilutive securities (in shares)                 1,291,000   1,356,000
Stock-Based Compensation                      
Stock-based compensation expense                 $ 13,651,000 $ 7,848,000 $ 4,869,000
Basic numerator:                      
Net income (loss) attributable to common stockholders for basic net income (loss) per share                 $ (48,925,000) $ 23,625,000 $ (17,592,000)
Denominator:                      
Weighted average common shares outstanding, basic                 46,817,756 41,267,329 39,015,131
Net income (loss) per common share, basic (in dollars per share) $ (0.25) $ (0.33) $ (0.15) $ (0.31) $ (0.21) $ (0.20) $ 1.16 $ (0.16) $ (1.05) $ 0.57 $ (0.45)
Diluted numerator:                      
Net income (loss) attributable to common stockholders for diluted net income (loss) per share                 $ (48,925,000) $ 23,625,000 $ (17,592,000)
Denominator                      
Weighted average common shares outstanding, basic                 46,817,756 41,267,329 39,015,131
Dilutive effect of conversion of convertible preferred stock                   1,121,538  
Weighted average common shares outstanding, diluted                 46,817,756 42,388,867 39,015,131
Net income (loss) per common share, diluted (in dollars per share) $ (0.25) $ (0.33) $ (0.15) $ (0.31) $ (0.21) $ (0.20) $ 1.13 $ (0.16) $ (1.05) $ 0.56 $ (0.45)
Employee stock options                      
Net Income (Loss) Per Share                      
Anti-dilutive securities (in shares)                 1,291,000   1,281,000
Employee Stock Purchase Plan                      
Net Income (Loss) Per Share                      
Anti-dilutive securities (in shares)                     75,000
Stock-Based Compensation                      
Stock-based compensation expense                 $ 498,000 $ 378,000