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Prior-Period Financial Statementss - (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | ---
Sep. 30, 2018 | Sep. 30, 2017 | Jun. 30, 2016 | Sep. 30, 2018 | Sep. 30, 2017 | Dec. 31, 2017 | Dec. 31, 2016
Revenue |  |  |  |  |  |  |
Collaborations, licenses and milestones | $ 29,039 |  |  | $ 29,039 | $ 16,000 |  |
ASU 2014-09 | As Reported Before ASC Topic 606 |  |  |  |  |  |  |
Revenue |  |  |  |  |  |  |
Collaborations, licenses and milestones |  | $ 7,090 |  |  | 24,771 |  |
ASU 2014-09 | Effect of Adoption of ASC Topic 606 |  |  |  |  |  |  |
Revenue |  |  |  |  |  |  |
Collaborations, licenses and milestones |  | $ (7,090) |  |  | $ (8,771) |  |
ASU 2014-09 | Collaboration |  |  |  |  |  |  |
Revenue |  |  |  |  |  |  |
Collaborations, licenses and milestones |  |  |  |  |  | $ 20,500 | $ 6,250
ASU 2014-09 | License |  |  |  |  |  |  |
Revenue |  |  |  |  |  |  |
Prior revenue recognition period |  |  |  | 5 years |  |  |
Collaborations, licenses and milestones |  |  | $ 11,300 |  |  |  |

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