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Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2021	Mar. 31, 2020
Cash flows from operating activities
Net loss	$ (2,487)	$ (8,074)
Adjustments to reconcile net loss to net cash (used in) provided by operating activities:
Depreciation and amortization	1,638	1,373
Amortization of premium (accretion of discount) on marketable securities	865	(573)
Stock-based compensation	8,293	6,512
Abandonment of capitalized intangible assets	193	28
Equity received in connection with license agreement		(4,589)
Change in fair value of equity security	(12,980)	2,336
Changes in operating assets and liabilities:
Accounts receivable	(1,082)	14,749
Interest receivable	311	215
Contract asset and deposits	(62)
Prepaid expenses and other current assets	(3,438)	71
Accounts payable	(1,291)	124
Accrued expenses	(5,090)	(1,703)
Lease liabilities and right-of-use (ROU) assets	(42)	(54)
Deferred revenue	(14,794)	(955)
Net cash (used in) provided by operating activities	(29,966)	9,460
Cash flows from investing activities
Purchase of marketable securities	(84,139)	(142,477)
Purchase of intangible assets	(72)	(538)
Purchase of property and equipment	(1,951)	(2,073)
Proceeds from maturities and sale of marketable securities	124,210	157,653
Net cash provided by investing activities	38,048	12,565
Cash flows from financing activities
Proceeds from issuance of common stock upon exercise of stock awards	5,339	1,471
Net cash provided by financing activities	5,339	1,471
Net increase in cash and cash equivalents	13,421	23,496
Cash and cash equivalents, beginning of year	163,544	50,312
Cash and cash equivalents, end of year	176,965	73,808
Cash paid during the period for:
Interest	4	6
Supplemental disclosures of non-cash investing activities
Net unrealized gain (loss) on marketable securities available-for-sale	$ 23	$ (105)

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