<SEC-DOCUMENT>0001415889-21-001300.txt : 20210303
<SEC-HEADER>0001415889-21-001300.hdr.sgml : 20210303
<ACCEPTANCE-DATETIME>20210303200111
ACCESSION NUMBER:		0001415889-21-001300
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20210303
FILED AS OF DATE:		20210303
DATE AS OF CHANGE:		20210303

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Dahiyat Bassil I
		CENTRAL INDEX KEY:			0001591312

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36182
		FILM NUMBER:		21711838

	MAIL ADDRESS:	
		STREET 1:		C/O XENCOR, INC.
		STREET 2:		111 WEST LEMON AVENUE
		CITY:			MONROVIA
		STATE:			CA
		ZIP:			91016

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Xencor Inc
		CENTRAL INDEX KEY:			0001326732
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				201622502
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		111 WEST LEMON AVE
		CITY:			MONROVIA
		STATE:			CA
		ZIP:			91016
		BUSINESS PHONE:		626-305-5900

	MAIL ADDRESS:	
		STREET 1:		111 WEST LEMON AVE
		CITY:			MONROVIA
		STATE:			CA
		ZIP:			91016
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>form4-03032021_080345.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2021-03-03</periodOfReport>

    <issuer>
        <issuerCik>0001326732</issuerCik>
        <issuerName>Xencor Inc</issuerName>
        <issuerTradingSymbol>XNCR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001591312</rptOwnerCik>
            <rptOwnerName>Dahiyat Bassil I</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O XENCOR, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>111 W. LEMON AVE</rptOwnerStreet2>
            <rptOwnerCity>MONROVIA</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>91016</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
            <isOfficer>true</isOfficer>
            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle>PRESIDENT &amp; CEO</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2021-03-03</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>2850</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>44.8803</value>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>141064</value>
                    <footnoteId id="F3"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">Represents the disposition of shares that were sold to pay withholding taxes upon vesting of 7,868 restricted stock units.</footnote>
        <footnote id="F2">The weighted average sale price for the transaction reported was $44.8803, and the range of prices were between $44.8801 and $45.15. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided.</footnote>
        <footnote id="F3">Includes the following shares acquired by the reporting person pursuant to the Issuer's Employee Stock Purchase Plan: 232 shares acquired in June 2020 and 178 shares acquired in December 2020.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Celia E. Eckert, Attorney-in-Fact</signatureName>
        <signatureDate>2021-03-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
