<SEC-DOCUMENT>0001415889-21-001435.txt : 20210310
<SEC-HEADER>0001415889-21-001435.hdr.sgml : 20210310
<ACCEPTANCE-DATETIME>20210310200054
ACCESSION NUMBER:		0001415889-21-001435
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20210308
FILED AS OF DATE:		20210310
DATE AS OF CHANGE:		20210310

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Desjarlais John R
		CENTRAL INDEX KEY:			0001591313

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36182
		FILM NUMBER:		21731449

	MAIL ADDRESS:	
		STREET 1:		C/O XENCOR, INC.
		STREET 2:		111 WEST LEMON AVENUE
		CITY:			MONROVIA
		STATE:			CA
		ZIP:			91016

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Xencor Inc
		CENTRAL INDEX KEY:			0001326732
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				201622502
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		111 WEST LEMON AVE
		CITY:			MONROVIA
		STATE:			CA
		ZIP:			91016
		BUSINESS PHONE:		626-305-5900

	MAIL ADDRESS:	
		STREET 1:		111 WEST LEMON AVE
		CITY:			MONROVIA
		STATE:			CA
		ZIP:			91016
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>form4-03102021_080313.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2021-03-08</periodOfReport>

    <issuer>
        <issuerCik>0001326732</issuerCik>
        <issuerName>Xencor Inc</issuerName>
        <issuerTradingSymbol>XNCR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001591313</rptOwnerCik>
            <rptOwnerName>Desjarlais John R</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O XENCOR, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>111 W. LEMON AVE</rptOwnerStreet2>
            <rptOwnerCity>MONROVIA</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>91016</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>false</isDirector>
            <isOfficer>true</isOfficer>
            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle>SR. VICE PRESIDENT &amp; CSO</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2021-03-08</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>10421</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>102209</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Options</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>43</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2021-03-08</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>62523</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2031-03-08</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>62523</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>62523</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Represents restricted stock units that vest as follows: 1/3 of the shares vest on the first, second and third anniversaries of the date of grant.</footnote>
        <footnote id="F2">25% of the shares subject to the option shall vest on the one year anniversary of March 8, 2021 (the &quot;Vesting Commencement Date&quot;) and 1/48th of the shares shall vest monthly thereafter, such that the option shall be fully vested on the four year anniversary of the Vesting Commencement Date.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Celia E. Eckert, Attorney-in-Fact</signatureName>
        <signatureDate>2021-03-10</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>ex24-03102021_080316.htm
<TEXT>
<!DOCTYPE html PUBLIC "-//IETF//DTD HTML//EN">
<html><head><title>ex24-03102021_080316.htm</title></head><body style="margin-top:0;font-family:Times New Roman; font-size:10pt; color:#000000">
<p style="margin-top:5.733px; margin-bottom:0px; padding-left:226.867px; padding-right:227.933px; font-size:12pt" align="center"><b>POWER OF ATTORNEY</b></p>
<p style="margin-top:0.333px; margin-bottom:0px"><br></p>
<p style="margin:0px; padding-left:6.667px; padding-right:7.667px; text-indent:47.933px; font-size:12pt" align="justify">Know all by these presents, that the undersigned hereby constitutes and appoints each of Bassil I. Dahiyat, John J. Kuch and Celia Eckert of Xencor, Inc. (the <b><i><font style="font-family:Arial Unicode MS,Times New Roman">&ldquo;</font>Company<font style="font-family:Arial Unicode MS,Times New Roman">&rdquo;</font></i></b>), signing individually, the undersigned<font style="font-family:Arial Unicode MS,Times New Roman">&rsquo;</font>s true and lawful attorney-in-fact and agent to:</p>
<p style="margin-top:0.667px; margin-bottom:0px"><br></p>
<p style="margin-top:0.067px;margin-bottom:-1pt;font-size:1pt"></p><p style="margin-top:0px; margin-bottom:-2px; text-indent:11.933px; width:36.733px; font-size:11pt; float:left">(1)</p>
<p style="margin:0px; padding-left:36.733px; padding-right:7.667px; text-indent:-2px; font-size:12pt" align="justify">execute for and on behalf of the undersigned, an officer, director or holder of 10% of more of a registered class of securities of the Company, Forms 3, 4 and 5 in accordance with Section 16(a) of the Securities Exchange Act of 1934, as amended (the <b><i><font style="font-family:Arial Unicode MS,Times New Roman">&ldquo;</font>Exchange Act<font style="font-family:Arial Unicode MS,Times New Roman">&rdquo;</font></i></b>) and the rules thereunder;</p>
<p style="margin-top:0.6px; margin-bottom:0px; clear:left"><br></p>
<p style="margin-top:0.067px;margin-bottom:-1pt;font-size:1pt"></p><p style="margin-top:0px; margin-bottom:-2px; text-indent:11.933px; width:36.733px; font-size:11pt; float:left">(2)</p>
<p style="margin:0px; padding-left:36.733px; padding-right:7.8px; text-indent:-2px; font-size:12pt" align="justify">do and perform any and all acts for and on behalf of the undersigned that may be necessary or desirable to complete and execute such Form 3, 4 or 5, complete and execute any amendment or amendments thereto, and timely file such forms or amendments with the United States Securities and Exchange Commission and any stock exchange or similar authority; and</p>
<p style="margin-top:0.667px; margin-bottom:0px; clear:left"><br></p>
<p style="margin-top:0px; margin-bottom:-2px; text-indent:11.933px; width:36.733px; font-size:11pt; float:left">(3)</p>
<p style="margin:0px; padding-left:36.733px; padding-right:7.6px; text-indent:-2px; font-size:12pt" align="justify">take any other action of any nature whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit, in the best interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve in such attorney-in-fact<font style="font-family:Arial Unicode MS,Times New Roman">&rsquo;</font>s discretion.</p>
<p style="margin-top:0.667px; margin-bottom:0px; clear:left"><br></p>
<p style="margin-top:0.067px; margin-bottom:0px; padding-left:6.667px; padding-right:7.667px; text-indent:47.933px; font-size:12pt" align="justify">The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that such attorney-in-fact, or such attorney-in- fact<font style="font-family:Arial Unicode MS,Times New Roman">&rsquo;</font>s substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted. The undersigned acknowledges that each of the foregoing attorneys-in-fact, in serving in such capacity at the request of the undersigned, is not assuming, nor is the Company assuming, any of the undersigned<font style="font-family:Arial Unicode MS,Times New Roman">&rsquo;</font>s responsibilities to comply with Section 16 of the Exchange Act.</p>
<p style="margin-top:0.667px; margin-bottom:0px"><br></p>
<p style="margin-top:0.067px; margin-bottom:0px; padding-left:6.667px; padding-right:7.667px; text-indent:47.933px; font-size:12pt" align="justify">This Power of Attorney shall remain in full force and effect until the earliest to occur of (a) the undersigned is no longer required to file Forms 3, 4 and 5 with respect to the undersigned<font style="font-family:Arial Unicode MS,Times New Roman">&rsquo;</font>s holdings of and transactions in securities issued by the Company, (b) revocation by the undersigned in a signed writing delivered to the foregoing attorney-in-fact or (c) until such attorney-in-fact shall no longer be employed by the Company.</p>
<p style="margin-top:0.733px; margin-bottom:0px"><br></p>
<p style="margin:0px; text-indent:48px; font-size:12pt" align="justify"><b>I</b><b style="font-size:9.5pt;font-weight:normal;"><b>N</b></b><b style="font-size:9.5pt;font-weight:normal;"><b> </b></b>W<b style="font-size:9.5pt;font-weight:normal;"><b>ITNESS</b></b><b style="font-size:9.5pt;font-weight:normal;"><b> </b></b>W<b style="font-size:9.5pt;font-weight:normal;"><b>HEREOF</b></b>, the undersigned has caused this Power of Attorney to be executed as of this 10th day of March, 2021.</p>
<p style="line-height:1pt; margin:0px"><br></p>
<p style="margin:0px"><br></p>
<p style="margin-top:0.4px; margin-bottom:0px; text-indent:336px; font-size:12pt"><u>/s/ John R. Desjarlais</u></p>
<p style="margin:0px; text-indent:336px; font-size:12pt">John R. Desjarlais, Ph.D.</p>
<p style="margin:0px"><br></p>
<p style="margin:0px"><br></p>
<p style="margin:0px"><br></p>
<p style="margin-top:0.2px; margin-bottom:0px"><br></p>
<p style="margin-top:4.533px; margin-bottom:0px; padding-left:6.667px; font-size:8pt">210849937 v1</p>
<p style="margin-top:6.267px; margin-bottom:0px"><br></p>
<p style="margin-top:6.267px; margin-bottom:0px"><br></p>
</body></html>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
