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Marketable Debt and Equity Securities - Equity Securities with Readily Determinable Fair Value (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022	Dec. 31, 2022
Equity Securities
Net gains (losses) recognized on equity securities	$ 288	$ (6,545)	$ (2,610)	$ (9,974)
Equity securities with readily determinable fair value	39,995		39,995		$ 42,431
Common Stock
Equity Securities
Equity securities with readily determinable fair value	39,995		39,995		42,431
Astria/Catabasis | Common Stock
Equity Securities
Equity securities with readily determinable fair value	5,813		5,813		9,529
INmune | Common Stock
Equity Securities
Equity securities with readily determinable fair value	17,121		17,121		11,954
Viridian | Common Stock
Equity Securities
Equity securities with readily determinable fair value	$ 17,061		$ 17,061		$ 20,948

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- Definition

Amount of investment in equity security measured at fair value with change in fair value recognized in net income (FV-NI), classified as current.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(2))
-Publisher FASB
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Reference 2: http://www.xbrl.org/2003/role/exampleRef
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Reference 3: http://www.xbrl.org/2003/role/disclosureRef
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Amount of unrealized and realized gain (loss) on investment in equity security measured at fair value with change in fair value recognized in net income (FV-NI).

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 944
-SubTopic 220
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
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Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
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