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Marketable Debt and Equity Securities - Equity Securities without Readily Determinable Fair Value (Details) - Preferred Stock - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
Equity securities without readily determinable fair value
Equity shares estimated fair value	$ 64,209	$ 54,383
Astria/Catabasis
Equity securities without readily determinable fair value
Equity shares estimated fair value	0	174
Zenas
Equity securities without readily determinable fair value
Equity shares estimated fair value	64,209	$ 54,209
Zenas | Milestone | License Agreement
Equity securities without readily determinable fair value
Equity shares estimated fair value	$ 10,000

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- Definition

Amount of investment in equity security without readily determinable fair value.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 321
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Subparagraph (a)
-Publisher FASB
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+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 321
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147479536/321-10-50-3

Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
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-Section 50
-Paragraph 3
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147479536/321-10-50-3

Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef
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-Section 50
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