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Marketable Debt and Equity Securities - Equity Securities Transactions (Details) - USD ($)
$ in Thousands
Jun. 30, 2023
Dec. 31, 2022
Preferred Stock    
Equity Securities    
Equity shares estimated fair value $ 64,209 $ 54,383
Astria/Catabasis | Preferred Stock    
Equity Securities    
Equity shares estimated fair value 0 174
Zenas | Preferred Stock    
Equity Securities    
Equity shares estimated fair value $ 64,209 $ 54,209
License Agreement | INmune | Common Stock    
Equity Securities    
Number of shares owned 1,885,533  
License Agreement | Zenas | Preferred Stock | Milestone    
Equity Securities    
Equity shares estimated fair value $ 10,000  
Technology License Agreement | Viridian | Common Stock    
Equity Securities    
Number of shares owned 717,144