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Marketable Debt and Equity Securities - Equity Securities Transactions (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Equity Securities
Unrealized gain (loss) on equity securities	$ (10,015)	$ 288	$ (10,529)	$ (2,610)
License | Astria | Common Stock
Equity Securities
Sale of common stock (in shares)	443,909		443,909
Number of shares owned (in shares)	253,958		253,958
License | INmune
Equity Securities
Unrealized gain (loss) on equity securities	$ (5,500)	4,900	$ (4,600)	5,200
License | INmune | Common Stock
Equity Securities
Number of shares owned (in shares)	1,885,533		1,885,533
Technology License Agreement | Astria/Catabasis
Equity Securities
Unrealized gain (loss) on equity securities	$ (1,300)	(3,500)	$ 400	(3,900)
Technology License Agreement | Viridian
Equity Securities
Unrealized gain (loss) on equity securities	$ (3,200)	$ (1,200)	$ (6,300)	$ (3,900)
Technology License Agreement | Viridian | Common Stock
Equity Securities
Number of shares owned (in shares)	717,144		717,144

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