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Collaboration and Licensing Agreements - Narrative (Details)
1 Months Ended 3 Months Ended 6 Months Ended
Oct. 01, 2021
Jul. 31, 2024
USD ($)
Oct. 31, 2021
USD ($)
Feb. 28, 2019
USD ($)
Jan. 31, 2013
program
Jun. 30, 2024
USD ($)
Jun. 30, 2023
USD ($)
Dec. 31, 2019
target
Jun. 30, 2024
USD ($)
Jun. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
Collaboration research and licensing agreements                      
Receivable           $ 22,073,000     $ 22,073,000   $ 11,290,000
Unrealized gain (loss) on equity securities           (10,015,000) $ 288,000   (10,529,000) $ (2,610,000)  
Impairment on equity securities           (220,000) 0   20,430,000 0  
Deferred revenue           0 7,900,000   0 7,900,000  
Collaborations, milestones, and royalties           16,960,000 45,523,000   29,765,000 64,485,000  
Royalties                      
Collaboration research and licensing agreements                      
Collaborations, milestones, and royalties           0 13,300,000   100,000 27,000,000.0  
Milestone                      
Collaboration research and licensing agreements                      
Collaborations, milestones, and royalties           0 10,000,000.0   500,000 15,000,000.0  
Alexion                      
Collaboration research and licensing agreements                      
Collaborations, milestones, and royalties           6,900,000 11,200,000   16,300,000 21,600,000  
MorphoSys                      
Collaboration research and licensing agreements                      
Collaborations, milestones, and royalties           1,600,000 2,000,000.0   4,400,000 3,900,000  
Mabgeek                      
Collaboration research and licensing agreements                      
Collaborations, milestones, and royalties           1,500,000 0   1,500,000 0  
Vir                      
Collaboration research and licensing agreements                      
Collaborations, milestones, and royalties           0 100,000   100,000 1,500,000  
Zenas                      
Collaboration research and licensing agreements                      
Impairment on equity securities             0   20,400,000 0  
Collaborations, milestones, and royalties           0 10,000,000.0   0 10,000,000.0  
Zenas | Preferred Stock                      
Collaboration research and licensing agreements                      
Equity shares estimated fair value           43,780,000     43,780,000   64,210,000
Third Party Licensee                      
Collaboration research and licensing agreements                      
Collaborations, milestones, and royalties           7,000,000.0 0   7,000,000.0 0  
Option and License agreement | Alexion                      
Collaboration research and licensing agreements                      
Number of different target programs | program         1            
Receivable           0     0    
Deferred revenue           0     0    
Option and License agreement | Alexion | Royalties                      
Collaboration research and licensing agreements                      
Revenue recognized           6,900,000 11,200,000   16,300,000 21,600,000  
Technology License Agreement | Mabgeek                      
Collaboration research and licensing agreements                      
Deferred revenue           0     0    
Collaborations, milestones, and royalties           1,500,000     1,500,000    
Technology License Agreement | Vega                      
Collaboration research and licensing agreements                      
Revenue recognized     $ 500,000                
Collaborations, milestones, and royalties           0 0   500,000 0  
Technology License Agreement | Gale                      
Collaboration research and licensing agreements                      
Transaction price           7,500,000     7,500,000    
Service agreement charges           4,600,000     8,000,000.0    
Technology License Agreement | Gale | Subsequent Event                      
Collaboration research and licensing agreements                      
Payments for repurchase of preferred stock and preference stock   $ 3,000,000.0                  
Collaboration and License Agreement | Genentech                      
Collaboration research and licensing agreements                      
Revenue recognized           0 0   0 0  
Initial cost-sharing percentage       45.00%              
Royalty milestones       $ 600,000,000              
Collaboration and License Agreement | Genentech | Development-based                      
Collaboration research and licensing agreements                      
Royalty milestones       115,000,000              
Collaboration and License Agreement | Genentech | Regulatory-based                      
Collaboration research and licensing agreements                      
Royalty milestones       185,000,000              
Collaboration and License Agreement | Genentech | Sales-based                      
Collaboration research and licensing agreements                      
Royalty milestones       $ 300,000,000              
Collaboration and License Agreement | Genentech | XmAb24306                      
Collaboration research and licensing agreements                      
Collaborative arrangement receivable (payable) related to cost sharing development activities           (7,600,000)     (7,600,000)    
Collaboration and License Agreement | Genentech | Research service                      
Collaboration research and licensing agreements                      
Deferred revenue           0     0    
Collaboration and License Agreement | Janssen                      
Collaboration research and licensing agreements                      
Revenue recognized           0 0   0 0  
Deferred revenue           0     0    
Collaboration and License Agreement | MorphoSys                      
Collaboration research and licensing agreements                      
Deferred revenue           0     0    
Collaboration and License Agreement | MorphoSys | Royalties                      
Collaboration research and licensing agreements                      
Revenue recognized           1,600,000 2,000,000.0   4,400,000 3,900,000  
Receivable           2,100,000     2,100,000    
License | Zenas                      
Collaboration research and licensing agreements                      
Revenue recognized           0 10,000,000.0   0 10,000,000.0  
Deferred revenue           0     0    
License | Zenas | Milestone | Preferred Stock                      
Collaboration research and licensing agreements                      
Equity shares estimated fair value                     $ 10,000,000.0
Second Collaboration And License Agreement | Janssen                      
Collaboration research and licensing agreements                      
Revenue recognized           0 22,200,000   0 27,500,000  
Receivable           5,200,000     5,200,000    
Deferred revenue           0     0    
Research license term 2 years                    
Second Collaboration And License Agreement | Janssen | Maximum                      
Collaboration research and licensing agreements                      
Percentage of responsibility for development costs 20.00%                    
Second Collaboration And License Agreement | Janssen | Minimum                      
Collaboration research and licensing agreements                      
Share development percentage 80.00%                    
Patent License Agreement | Vir                      
Collaboration research and licensing agreements                      
Number of different target programs | target               2      
Receivable           0     0    
Deferred revenue           0     0    
Patent License Agreement | Vir | Royalties                      
Collaboration research and licensing agreements                      
Revenue recognized             $ 100,000   100,000 $ 1,500,000  
Patent License Agreement | Third Party Licensee                      
Collaboration research and licensing agreements                      
Receivable           7,000,000.0     7,000,000.0    
Deferred revenue           0     0    
Collaborations, milestones, and royalties           $ 7,000,000.0     $ 7,000,000.0