<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>doc1.txt
<DESCRIPTION>POWER OF ATTORNEY (PUBLIC): POA
<TEXT>
POWER OF ATTORNEY

Know all by these presents, that the undersigned hereby
constitutes and appoints each of Bassil I. Dahiyat, Bart
Jan Cornelissen and Celia E. Eckert of Xencor, Inc. (the
?Company?), signing individually, the undersigned?s true
and lawful attorney-in-fact and agent to:

(1) execute for and on behalf of the undersigned, an
officer, director and/or holder of 10% of more of a
registered class of securities of the Company, Forms
3, 4 and 5 in accordance with Section 16(a) of the
Securities Exchange Act of 1934, as amended (the ?Exchange
Act?) and the rules promulgated thereunder or Forms 144 in
accordance with Rule 144 (?Rule 144?) under the Securities
Act of 1933, as amended;

(2) do and perform any and all acts for and on behalf of
the undersigned that may be necessary or desirable to
complete and execute any such Form 3, 4, 5 and 144,
omplete and execute any amendment or amendments thereto,
and timely file such forms or amendments with the United
States Securities and Exchange Commission and any stock
exchange or similar authority, as required; and

(3) take any other action of any nature whatsoever in
connection with the foregoing which, in the opinion of
any such attorney-in-fact, may be of benefit to, in the
best interest of, or legally required by, the undersigned,
it being understood that the documents executed by such
attorney-in-fact on behalf of the undersigned pursuant to
this Power of Attorney shall be in such form and shall
contain such terms and conditions as such attorney-in-fact
may approve in such attorney-in-fact?s discretion.

The undersigned hereby grants to each such attorney-in-fact
full power and authority to do and perform any and every
act and thing whatsoever requisite, necessary, or proper to
be done in the exercise of any of the rights and powers
herein granted, as fully to all intents and purposes as the
undersigned might or could do if personally present, with
full power of substitution or revocation, hereby ratifying
and confirming all that such attorney-in-fact, or such
attorney-in-fact?s substitute or substitutes, shall
lawfully do or cause to be done by virtue of this power
of attorney and the rights and powers herein granted. The
undersigned acknowledges that the foregoing attorneys-in-
fact, in serving in such capacity at the request of the
undersigned, are not assuming, nor is the Company assuming,
any of the undersigned?s responsibilities to comply with
Section 16 of the Exchange Act or Rule 144.

This Power of Attorney shall remain in full force and
effect with respect to the undersigned until the earliest
to occur of (a) such date that the undersigned is no
longer required to file Forms 3, 4, 5 and 144 with respect
to the undersigned?s holdings of and transactions in
securities issued by the Company or (b) revocation by the
undersigned in a signed writing delivered to the Company
and foregoing attorneys-in-fact. This Power of Attorney
shall terminate with respect to each of the foregoing
attorneys-in-fact at such time as such attorney-in-fact is
no longer employed by the Company.

IN WITNESS WHEREOF, the undersigned has caused this Power
of Attorney to be executed as of this 19th day of February,
2025.

/s/ Barbara J. Klencke, M.D.
Barbara J. Klencke, M.D.
</TEXT>
</DOCUMENT>
