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Note 3 - Summary of Significant Accounting Policies (Details Textual) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | ---
Dec. 31, 2024 | Mar. 31, 2024 | Oct. 31, 2023 | Sep. 30, 2022 | Nov. 30, 2021 | Mar. 31, 2022 | Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2019 | Jun. 30, 2022 | Dec. 31, 2021
Accounts Receivable, Allowance for Credit Loss | $ 238 |  |  |  |  |  | $ 238 | $ 129 |  |  |  |
Inventory Valuation Reserves | 605 |  |  |  |  |  | 605 | 76 |  |  |  |
Payments to Acquire Intangible Assets |  |  |  |  |  |  | 9,988 | 775 | $ 2,750 |  |  |
Finite-Lived Intangible Assets, Accumulated Amortization | 2,381 |  |  |  |  |  | 2,381 | 1,286 |  |  |  |
Amortization of Intangible Assets |  |  |  |  |  |  | 1,096 | 790 | 1,617 |  |  |
Impairment, Long-Lived Asset, Held-for-Use |  |  |  |  |  |  | 0 | 0 | 0 |  |  |
Finance Lease, Liability | 0 |  |  |  |  |  | $ 0 | $ 0 |  |  |  |
Percentage for Valuation Reserve Against Deferred Tax Assets |  |  |  |  |  |  | 100.00% | 100.00% |  |  |  |
Unrecognized Tax Benefits | 382 |  |  |  |  |  | $ 382 | $ 0 | $ 0 |  |  | $ 0
Unrecognized Tax Benefits that Would Impact Effective Tax Rate | $ 0 |  |  |  |  |  | 0 | 0 |  |  |  |
Carglumic Acid Product Rights [Member] |  |  |  |  |  |  |  |  |  |  |  |
Payments to Acquire Intangible Assets |  |  |  |  | $ 3,250 |  |  |  |  |  |  |
Finite-Lived Intangible Asset, Useful Life (Year) |  |  |  |  | 10 years |  |  |  |  |  |  |
Biorphen [Member] |  |  |  |  |  |  |  |  |  |  |  |
Payments to Acquire Intangible Assets |  |  |  |  |  |  |  |  |  | $ 750 |  |
Finite-Lived Intangible Asset, Useful Life (Year) |  |  |  |  |  |  |  |  |  | 5 years |  |
Finite-Lived Intangible Assets, Accumulated Amortization |  |  |  |  |  |  |  |  |  |  | $ 275 |
Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year |  |  |  |  |  |  |  | $ 75 |  |  |  |
Rezipres Product [Member] |  |  |  |  |  |  |  |  |  |  |  |
Payments to Acquire Intangible Assets |  |  |  |  |  | $ 750 |  |  |  |  |  |
Finite-Lived Intangible Asset, Useful Life (Year) |  |  |  |  |  | 5 years |  |  |  |  |  |
Finite-Lived Intangible Assets, Accumulated Amortization |  |  |  |  |  |  |  |  |  |  | $ 738 |
Betaine Anhydrous Product Rights [Member] |  |  |  |  |  |  |  |  |  |  |  |
Payments to Acquire Intangible Assets |  |  |  | $ 2,125 |  |  |  |  |  |  |  |
Finite-Lived Intangible Asset, Useful Life (Year) |  |  |  | 5 years |  |  |  |  |  |  |  |
Nitisinone Product Rights [Member] |  |  |  |  |  |  |  |  |  |  |  |
Payments to Acquire Intangible Assets |  |  | $ 650 |  |  |  |  |  |  |  |  |
Finite-Lived Intangible Asset, Useful Life (Year) |  |  | 5 years |  |  |  |  |  |  |  |  |
PKU GoLike [Member] |  |  |  |  |  |  |  |  |  |  |  |
Payments to Acquire Intangible Assets |  | $ 1,868 |  |  |  |  |  |  |  |  |  |
Finite-Lived Intangible Asset, Useful Life (Year) |  | 10 years |  |  |  |  |  |  |  |  |  |
Increlex [Member] |  |  |  |  |  |  |  |  |  |  |  |
Payments to Acquire Intangible Assets |  |  |  |  |  |  | $ 21,250 |  |  |  |  |
Finite-Lived Intangible Asset, Useful Life (Year) | 10 years |  |  |  |  |  | 10 years |  |  |  |  |
GALZIN [Member] |  |  |  |  |  |  |  |  |  |  |  |
Payments to Acquire Intangible Assets | $ 8,119 |  |  |  |  |  |  |  |  |  |  |
Finite-Lived Intangible Asset, Useful Life (Year) | 10 years |  |  |  |  |  | 10 years |  |  |  |  |
Furniture and Fixtures [Member] |  |  |  |  |  |  |  |  |  |  |  |
Property, Plant and Equipment, Useful Life (Year) | 5 years |  |  |  |  |  | 5 years |  |  |  |  |
Increlex [Member] |  |  |  |  |  |  |  |  |  |  |  |
Inventory, Raw Materials, Gross | $ 5,000 |  |  |  |  |  | $ 5,000 |  |  |  |  |
Product Concentration Risk [Member] | Revenue Benchmark [Member] | AnovoRx [Member] |  |  |  |  |  |  |  |  |  |  |  |
Concentration Risk, Percentage |  |  |  |  |  |  | 93.60% | 78.20% | 45.50% |  |  |
Customer Concentration Risk [Member] | Accounts Receivable [Member] | AnovoRx [Member] |  |  |  |  |  |  |  |  |  |  |  |
Concentration Risk, Percentage |  |  |  |  |  |  | 96.20% | 97.40% |  |  |  |

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