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Note 3 - Summary of Significant Accounting Policies (Details Textual) - USD ($)
$ in Thousands
 1 Months Ended 9 Months Ended 12 Months Ended
Dec. 31, 2024
Mar. 31, 2024
Oct. 31, 2023
Sep. 30, 2022
Nov. 30, 2021
Sep. 30, 2025
Sep. 30, 2024
Dec. 31, 2024
Accounts Receivable, Allowance for Credit Loss $ 238         $ 238   $ 238
Inventory Valuation Reserves 605         942   605
Depreciation           24 $ 12  
Payments to Acquire Intangible Assets           (0) 1,868  
Finite-Lived Intangible Assets, Accumulated Amortization 2,381         5,384   2,381
Amortization of Intangible Assets           3,003 753  
Impairment, Long-Lived Asset, Held-for-Use           0 $ 0  
Finance Lease, Liability $ 0         $ 0   $ 0
Percentage for Valuation Reserve Against Deferred Tax Assets           100.00%   100.00%
Carglumic Acid Product Rights [Member]                
Payments to Acquire Intangible Assets         $ 3,250      
Finite-Lived Intangible Asset, Useful Life (Year)         10 years      
Betaine Anhydrous Product Rights [Member]                
Payments to Acquire Intangible Assets       $ 2,125        
Finite-Lived Intangible Asset, Useful Life (Year)       5 years        
Nitisinone Product Rights [Member]                
Payments to Acquire Intangible Assets     $ 650          
Finite-Lived Intangible Asset, Useful Life (Year)     5 years          
PKU GoLike [Member]                
Payments to Acquire Intangible Assets   $ 1,868            
Finite-Lived Intangible Asset, Useful Life (Year)   10 years            
Increlex [Member]                
Payments to Acquire Intangible Assets               $ 21,250
Finite-Lived Intangible Asset, Useful Life (Year) 10 years             10 years
GALZIN [Member]                
Payments to Acquire Intangible Assets $ 8,119              
Finite-Lived Intangible Asset, Useful Life (Year) 10 years             10 years
Furniture and Fixtures [Member]                
Property, Plant and Equipment, Useful Life (Year)           5 years    
Increlex [Member]                
Inventory, Raw Materials, Gross $ 5,000             $ 5,000
Customer Concentration Risk [Member] | Revenue Benchmark [Member] | AnovoRx [Member]                
Concentration Risk, Percentage           85.80% 98.50%  
Customer Concentration Risk [Member] | Accounts Receivable [Member] | AnovoRx [Member]                
Concentration Risk, Percentage           65.80%   96.20%