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Note 4 - Long-term Debt (Details Textual)	1 Months Ended			3 Months Ended		9 Months Ended
	Sep. 30, 2024 USD ($) $ / shares shares	Aug. 31, 2020 USD ($) $ / shares shares	Nov. 30, 2019 USD ($) $ / shares shares	Sep. 30, 2025 USD ($) $ / shares shares	Sep. 30, 2024 USD ($) $ / shares shares	Sep. 30, 2025 USD ($) $ / shares shares	Sep. 30, 2024 USD ($) $ / shares shares	Dec. 31, 2024 USD ($) $ / shares	Nov. 13, 2019 USD ($)
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares				359,116		359,116
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares				$ 5.46		$ 5.46
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares				$ 0.001		$ 0.001		$ 0.001
Share Price (in dollars per share) | $ / shares	$ 6				$ 6		$ 6
Interest Expense, Operating and Nonoperating				$ 1,212,000	$ 211,000
Amortization of Debt Discount (Premium)				189,000	29,000	$ 521,000	$ 70,000
Accrued Liabilities, Current				9,117,000		9,117,000		$ 8,914,000
Debt Instrument, Variable Interest Rate, Type [Extensible Enumeration]	Secured Overnight Financing Rate (SOFR) [Member]
Liability, Interest and Exit Fees [Member]
Accrued Liabilities, Current				454,000		454,000		$ 182,000
Ipsen Biopharmaceuticals, Inc [Member]
Interest Expense, Operating and Nonoperating						350,000
Debt Instrument, Accrued Exit Fees	$ 70,000			70,000	$ 70,000	70,000	$ 70,000
Accounts Receivable, after Allowance for Credit Loss				5,000,000		5,000,000
SWK Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares		18,141	51,239
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares		$ 6.62	$ 5.86
Warrants and Rights Outstanding			$ 51,239
Fair Value Adjustment of Warrants		$ 94,000	$ 226,000
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares		$ 6.85	$ 5.75
Warrants and Rights Outstanding, Term (Year)		7 years	7 years
SWK Warrants [Member] | Measurement Input, Price Volatility [Member]
Warrants and Rights Outstanding, Measurement Input		0.95	0.95
SWK Warrants [Member] | Measurement Input, Expected Dividend Rate [Member]
Warrants and Rights Outstanding, Measurement Input		0	0
SWK Warrants [Member] | Measurement Input, Risk Free Interest Rate [Member]
Warrants and Rights Outstanding, Measurement Input		0.004	0.018
Common Stock Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares	289,736				289,736		289,736
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 5.32				$ 5.32		$ 5.32
Warrants and Rights Outstanding	$ 1,170,000				$ 1,170,000		$ 1,170,000
Common Stock Warrants [Member] | Measurement Input, Price Volatility [Member]
Warrants and Rights Outstanding, Measurement Input	63.8				63.8		63.8
Common Stock Warrants [Member] | Measurement Input, Expected Dividend Rate [Member]
Warrants and Rights Outstanding, Measurement Input	0				0		0
Common Stock Warrants [Member] | Measurement Input, Risk Free Interest Rate [Member]
Warrants and Rights Outstanding, Measurement Input	3.67				3.67		3.67
Common Stock Warrants [Member] | Measurement Input, Expected Term [Member]
Warrants and Rights Outstanding, Measurement Input	7				7		7
SWK Credit Agreement [Member]
Debt Instrument, Unamortized Discount				389,000		389,000
Debt Instrument, Accrued Exit Fees				756,000		756,000
SWK Credit Agreement [Member] | SWK Holdings Corporation [Member]
Debt Instrument, Face Amount									$ 10,000,000
The Amended Agreement [Member] | SWK Holdings Corporation [Member]
Line of Credit Facility, Maximum Borrowing Capacity	$ 30,000				$ 30,000		$ 30,000
Debt Instrument, Basis Spread on Variable Rate	6.75%
Debt Instrument, Periodic Payment, Principal	$ 3,000,000
Debt Instrument, Periodic Payment Terms, Balloon Payment to be Paid	$ 9,000,000				$ 9,000,000		$ 9,000,000
Debt Instrument, Exit Fee as a Percentage of Outstanding Amounts	5.00%				5.00%		5.00%
Debt Instrument, Unamortized Discount	$ 555,000			$ 555,000	$ 555,000	$ 555,000	$ 555,000

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