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Note 2 - Summary of Significant Accounting Policies - Schedule of Intangible Assets (Details) - USD ($) $ in Thousands | Mar. 31, 2026 | Feb. 28, 2026 | Dec. 31, 2025
--- | --- | --- | ---
Finite lived intangible, gross | $ 51,231 |  | $ 37,262
Intangible asset, accumulated amortization | 7,493 |  | 6,384
Intangible assets, net | $ 43,738 |  | $ 30,878
Carglumic Acid Product Rights [Member] |  |  |
Useful life (Year) | 10 years |  | 10 years
Finite lived intangible, gross | $ 3,250 |  | $ 3,250
Intangible asset, accumulated amortization | 1,435 |  | 1,354
Intangible assets, net | $ 1,815 |  | $ 1,896
Betaine Anhydrous Product Rights [Member] |  |  |
Useful life (Year) | 5 years |  | 5 years
Finite lived intangible, gross | $ 2,125 |  | $ 2,125
Intangible asset, accumulated amortization | 1,505 |  | 1,399
Intangible assets, net | $ 620 |  | $ 726
Nitisinone Product Rights [Member] |  |  |
Useful life (Year) | 5 years |  | 5 years
Finite lived intangible, gross | $ 650 |  | $ 650
Intangible asset, accumulated amortization | 325 |  | 292
Intangible assets, net | $ 325 |  | $ 358
PKU GoLike [Member] |  |  |
Useful life (Year) | 10 years |  | 10 years
Finite lived intangible, gross | $ 1,868 |  | $ 1,868
Intangible asset, accumulated amortization | 374 |  | 327
Intangible assets, net | $ 1,494 |  | $ 1,541
Increlex [Member] |  |  |
Useful life (Year) | 10 years |  | 10 years
Finite lived intangible, gross | $ 21,250 |  | $ 21,250
Intangible asset, accumulated amortization | 2,732 |  | 2,200
Intangible assets, net | $ 18,518 |  | $ 19,050
Glazin [Member] |  |  |
Useful life (Year) | 10 years |  | 10 years
Finite lived intangible, gross | $ 8,119 |  | $ 8,119
Intangible asset, accumulated amortization | 1,015 |  | 812
Intangible assets, net | 7,104 |  | $ 7,307
In Process Research and Development [Member] |  |  |
Finite lived intangible, gross | 1,000 |  |
Intangible asset, accumulated amortization | 0 |  |
Intangible assets, net | $ 1,000 |  |
Hemangeol [Member] |  |  |
Useful life (Year) | 10 years | 10 years |
Finite lived intangible, gross | $ 12,969 |  |
Intangible asset, accumulated amortization | 107 |  |
Intangible assets, net | $ 12,862 | $ 12,969 |

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