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Note 2 - Summary of Significant Accounting Policies (Tables)

3 Months Ended

Mar. 31, 2026

Notes Tables

Intangible Asset, Finite-Lived [Table Text Block]

		Useful Life			Purchase		Purchase				Accumulated				Carrying
Intangible assets as of March 31, 2026		(In years)			Date		Price				Amortization				Value
Carglumic Acid			10		November 2021		$	3,250			$	1,435			$	1,815
Betaine			5		September 2022			2,125				1,505				620
Nitisinone			5		October 2023			650				325				325
GoLike			10		March 2024			1,868				374				1,494
Increlex			10		December 2024			21,250				2,732				18,518
Galzin			10		December 2024			8,119				1,015				7,104
IPR&D asset					January 2026			1,000				—				1,000
HEMANGEOL			10		February 2026			12,969				107				12,862
							$	51,231			$	7,493			$	43,738

		Useful Life			Purchase		Purchase				Accumulated				Carrying
Intangible assets as of December 31, 2025		(In years)			Date		Price				Amortization				Value
Carglumic Acid			10		November 2021		$	3,250			$	1,354			$	1,896
Betaine			5		September 2022			2,125				1,399				726
Nitisinone			5		October 2023			650				292				358
GoLike			10		March 2024			1,868				327				1,541
Increlex			10		December 2024			21,250				2,200				19,050
Galzin			10		December 2024			8,119				812				7,307
							$	37,262			$	6,384			$	30,878

Intangible Asset, Finite-Lived, and Capitalized Cost, Software to be Sold, Leased, or Marketed, Estimated Amortization Expense [Table Text Block]

		Amortization
Year		Expense
Remainder of 2026		$	3,976
2027			5,377
2028			5,043
2029			4,946
2030			4,946
Thereafter			19,450
Total estimated amortization expense		$	43,738

X

- Definition

Tabular disclosure of finite-lived intangible asset. Excludes goodwill.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 350
-SubTopic 30
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482665/350-30-50-2

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Tabular disclosure of estimated amortization expense for finite-lived intangible asset and capitalized cost for software to be sold, leased, or marketed, expected to be recognized for each of five succeeding fiscal years. Excludes goodwill.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 350
-SubTopic 30
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (a)(3)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482665/350-30-50-2

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