XML 122 R49.htm IDEA: XBRL DOCUMENT v3.22.1
License Agreements - Additional Information (Details) - USD ($)
1 Months Ended 12 Months Ended
Jul. 20, 2021
Aug. 31, 2021
Jul. 31, 2021
May 31, 2021
Jan. 31, 2021
Apr. 30, 2020
Mar. 31, 2020
Feb. 29, 2020
Dec. 31, 2021
Dec. 31, 2020
License Agreements [Line Items]                    
In-process research and development                 $ 10,848,000 $ 71,745,000
Common Stock                    
License Agreements [Line Items]                    
Convertible preferred stock converted into shares of common stock                 71,263,685  
License Agreement | NiKang Therapeutics, Inc.                    
License Agreements [Line Items]                    
Upfront payment               $ 5,000,000.0    
Reimbursement of certain initial manufacturing costs               $ 400,000    
Payment for US patent application           $ 7,000,000.0        
Accrued development milestone payment                 $ 0 4,000,000.0
In-process research and development                 0 16,000,000.0
Ownership percentage of equity or assets               50.00%    
License Agreement | NiKang Therapeutics, Inc. | First Licensed Product | Maximum                    
License Agreements [Line Items]                    
Development and regulatory milestone payments obligation               $ 16,000,000.0    
Commercial milestone payments obligation               157,000,000.0    
License Agreement | NiKang Therapeutics, Inc. | Second Licensed Product                    
License Agreements [Line Items]                    
Development and regulatory milestone payments obligation               12,000,000.0    
Commercial milestone payments obligation               $ 151,000,000.0    
License Agreement | Katmai Pharmaceuticals, Inc.                    
License Agreements [Line Items]                    
Upfront payment             $ 5,700,000      
In-process research and development                 0 5,700,000
License Agreement | Katmai Pharmaceuticals, Inc. | Series B-1 Convertible Preferred Stock and Series B-2 Convertible Preferred Stock                    
License Agreements [Line Items]                    
Stock issued, value             2,700,000      
License Agreement | Katmai Pharmaceuticals, Inc. | Series B-1 Convertible Preferred Stock                    
License Agreements [Line Items]                    
Stock issued, value           $ 1,800,000        
Stock issued and sold           356,000        
License Agreement | Katmai Pharmaceuticals, Inc. | Series B-2 Convertible Preferred Stock                    
License Agreements [Line Items]                    
Stock issued, value         $ 900,000          
Stock issued and sold         118,666          
License Agreement | Katmai Pharmaceuticals, Inc. | Maximum                    
License Agreements [Line Items]                    
Development and regulatory milestone payments obligation             26,000,000.0      
Commercial milestone payments obligation             101,000,000.0      
License Agreement | LifeArc                    
License Agreements [Line Items]                    
Upfront payment           $ 0        
In-process research and development                 0 75,000
One-time license payment           75,000        
License Agreement | LifeArc | Maximum                    
License Agreements [Line Items]                    
Development and regulatory milestone payments obligation           $ 11,000,000.0        
Sales milestone payments obligation             $ 50,000,000.0      
License Agreement | The Regents                    
License Agreements [Line Items]                    
Upfront payment       $ 50,000            
In-process research and development                 7,200,000 $ 0
Sales milestone payments obligation       $ 2,000,000.0            
Percentage of third tier sublicensing fees       30.00%            
Cash payments in license agreement upon achievement of corporate milestone   $ 1,700,000                
License Agreement | The Regents | Common Stock                    
License Agreements [Line Items]                    
Stock issued and sold       944,945            
License Agreement | The Regents | Maximum                    
License Agreements [Line Items]                    
Development and regulatory milestone payments obligation       $ 6,400,000            
IPO                    
License Agreements [Line Items]                    
Stock issued, value                 316,999,000  
IPO | Common Stock                    
License Agreements [Line Items]                    
Stock issued, value                 $ 2,000  
Stock issued and sold 21,562,500               21,562,500  
Convertible preferred stock converted into shares of common stock 71,263,685   71,263,685              
IPO | License Agreement | Katmai Pharmaceuticals, Inc. | Series B-1 Convertible Preferred Stock and Series B-2 Convertible Preferred Stock                    
License Agreements [Line Items]                    
Conversion of convertible preferred stock into common stock             395,555