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Stock-based Compensation - Assumptions used to Determine Fair Value of Stock Option Grants (Details)
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Risk-free interest rate, minimum 1.46% 0.59%
Risk-free interest rate, maximum 1.74% 1.01%
Expected volatility, minimum 85.86% 83.40%
Expected volatility, maximum 85.99% 83.90%
Expected term (in years)   6 years 29 days
Expected dividend yield 0.00% 0.00%
Minimum    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected term (in years) 5 years 11 months 26 days  
Maximum    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected term (in years) 6 years 29 days