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Stock-based Compensation - Assumptions used to Determine Fair Value of Stock Option Grants and Stock to be Purchased under ESPP (Details) - Stock Options
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Risk-free interest rate, minimum 3.46% 1.46%
Risk-free interest rate, maximum 4.22% 1.74%
Expected volatility, minimum 85.52% 85.86%
Expected volatility, maximum 85.81% 85.99%
Expected dividend yield 0.00% 0.00%
Minimum    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Expected term (in years) 6 years 7 days 5 years 11 months 26 days
Maximum    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Expected term (in years) 6 years 25 days 6 years 29 days