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Stockholders' Equity and Stock-Based Compensation (Details 5) - $ / shares | 12 Months Ended
--- | ---
Dec. 31, 2018 | Dec. 31, 2017
Weighted Average Remaining Contractual Life - Years | 8 years 26 days | 8 years 4 months 14 days
Number of options outstanding | 5,604,154 | 3,976,884
Weighted Average Exercise Price Stock Options Outstanding | $ 2.72 | $ 3.58
Number of Awards Vested | 3,935,138 | 2,434,148
Weighted Average Exercise Price | $ 3.50 | $ 4.84
Weighted Average Remaining Contractual Life of Stock Options Vested | 7 years 5 months 1 day | 7 years 8 months 12 days
Range One [Member] |  |
Exercise price lower range limit | $ 0.90 | $ 1.05
Exercise price upper range limit | $ 1.04 | $ 2.00
Weighted Average Remaining Contractual Life - Years | 9 years 7 months 6 days | 9 years 6 months 21 days
Number of options outstanding | 1,616,402 | 2,528,666
Weighted Average Exercise Price Stock Options Outstanding | $ 0.90 | $ 1.18
Number of Awards Vested |  | 1,197,708
Weighted Average Exercise Price |  | $ 1.33
Weighted Average Remaining Contractual Life of Stock Options Vested | 0 years | 9 years 3 months 11 days
Range Two [Member] |  |
Exercise price lower range limit | $ 1.05 | $ 2.01
Exercise price upper range limit | $ 2.00 | $ 6.00
Weighted Average Remaining Contractual Life - Years | 8 years 6 months 25 days | 7 years 10 months 10 days
Number of options outstanding | 2,560,330 | 821,174
Weighted Average Exercise Price Stock Options Outstanding | $ 1.18 | $ 4.59
Number of Awards Vested | 2,507,716 | 651,429
Weighted Average Exercise Price | $ 1.18 | $ 4.58
Weighted Average Remaining Contractual Life of Stock Options Vested | 8 years 6 months 21 days | 7 years 10 months 10 days
Range Three [Member] |  |
Exercise price lower range limit | $ 2.01 | $ 6.01
Exercise price upper range limit | $ 6.00 | $ 20.00
Weighted Average Remaining Contractual Life - Years | 6 years 10 months 10 days | 5 years 1 month 13 days
Number of options outstanding | 813,583 | 505,694
Weighted Average Exercise Price Stock Options Outstanding | $ 4.59 | $ 7.47
Number of Awards Vested | 813,583 | 463,661
Weighted Average Exercise Price | $ 4.59 | $ 7.58
Weighted Average Remaining Contractual Life of Stock Options Vested | 6 years 10 months 10 days | 4 years 11 months 4 days
Range Four [Member] |  |
Exercise price lower range limit | $ 6.01 | $ 20.01
Exercise price upper range limit | $ 20.00 | $ 45.00
Weighted Average Remaining Contractual Life - Years | 4 years 1 month 27 days | 1 year 7 months 28 days
Number of options outstanding | 501,334 | 118,016
Weighted Average Exercise Price Stock Options Outstanding | $ 7.48 | $ 29.85
Number of Awards Vested | 501,334 | 118,016
Weighted Average Exercise Price | $ 7.48 | $ 29.85
Weighted Average Remaining Contractual Life of Stock Options Vested | 4 years 1 month 27 days | 1 year 7 months 28 days
Range Five [Member] |  |
Exercise price lower range limit | $ 20.01 | $ 45.01
Exercise price upper range limit | $ 43.25 | $ 72.00
Weighted Average Remaining Contractual Life - Years | 8 months 19 days | 2 months 5 days
Number of options outstanding | 112,505 | 3,334
Weighted Average Exercise Price Stock Options Outstanding | $ 2.72 | $ 50.25
Number of Awards Vested | 112,505 | 3,334
Weighted Average Exercise Price | $ 29.46 | $ 50.25
Weighted Average Remaining Contractual Life of Stock Options Vested | 8 months 19 days | 2 months 5 days

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- Definition The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iii) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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