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Income Taxes (Details 1) - USD ($) | 12 Months Ended
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Dec. 31, 2018 | Dec. 31, 2017
Income Taxes Details 1Abstract |  |
Tax benefit at U.S. federal and state statutory rates | $ (3,300,000) | $ (2,300,000)
Tax benefit at state statutory rates | 700,000 | 700,000
Change in Federal statutory rate | 0 | 9,600,000
Tax benefit from federal and state R&D tax credits | (200,000) | 0
Other | 0 | 400,000
Increase (decrease) in valuation allowance | 4,200,000 | (7,000,000)
Total provision for income tax benefit |  |

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