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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019
Operating Activities |  |
Net Loss | $ (14,417,266) | $ (10,676,747)
Adjustments to reconcile net loss from operations to net cash used in operating activities: |  |
Common stock issued for services and stock-based compensation | 70,341 | 822,820
Patent write-off and impairment loss | 1,169,644 | 0
Amortization of patents | 100,117 | 89,623
Equity in loss from joint venture | 0 | 3,321,737
Changes in operating working capital items |  |
Other receivable from joint venture | 400,000 | (306,747)
Prepaid expenses and other current assets | (125,089) | (10,626)
Accounts payable and accrued liabilities | 31,831 | 92,243
Accrued legal settlement costs | 4,200,000 | 0
Net Cash Used in Operating Activities | (8,570,421) | (6,667,697)
Investing Activities |  |
Investment in joint venture | 0 | (3,540,000)
Patents and trademarks | (210,436) | (221,063)
Net Cash Used in Investing Activities | (210,436) | (3,761,063)
Financing Activities |  |
Net proceeds from the issuance of common stock and exercise of stock options | 12,353,533 | 3,750,454
Net Cash Provided by Financing Activities | 12,353,533 | 3,750,454
Net Increase (Decrease) in Cash and Cash Equivalents | 3,572,676 | (6,678,306)
Cash and Cash Equivalents, Beginning of Year | 17,958,989 | 24,637,295
Cash and Cash Equivalents, End of Year | 21,531,665 | 17,958,989
Supplemental Disclosure of Cash Flow Information |  |
Interest paid | 0 | 0
Income taxes paid | 0 | 0
Non-Cash Financing Activities: |  |
Accumulated preferred stock dividend | 735,149 | 699,815
Conversion of Series A convertible preferred stock and payment of paid-in-kind dividends to common stock | 49,885 | 187,890
Common stock issued for services | $ 17,000 | $ 0

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