<SEC-DOCUMENT>0001287695-15-000515-index.html : 20151228
<SEC-HEADER>0001287695-15-000515.hdr.sgml : 20151225
<ACCEPTANCE-DATETIME>20151228114423
ACCESSION NUMBER:		0001287695-15-000515
CONFORMED SUBMISSION TYPE:	NSAR-B
PUBLIC DOCUMENT COUNT:		7
CONFORMED PERIOD OF REPORT:	20151031
FILED AS OF DATE:		20151228
DATE AS OF CHANGE:		20151228
EFFECTIVENESS DATE:		20151228

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BlackRock Multi-Sector Income Trust
		CENTRAL INDEX KEY:			0001562818
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		NSAR-B
		SEC ACT:		1940 Act
		SEC FILE NUMBER:	811-22774
		FILM NUMBER:		151308384

	BUSINESS ADDRESS:	
		STREET 1:		55 EAST 52ND STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10055
		BUSINESS PHONE:		800-882-0052

	MAIL ADDRESS:	
		STREET 1:		55 EAST 52ND STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10055

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BlackRock Fixed Income Strategic Opportunities
		DATE OF NAME CHANGE:	20121126
</SEC-HEADER>
<DOCUMENT>
<TYPE>NSAR-B
<SEQUENCE>1
<FILENAME>bitanswer.fil
<TEXT>
Document 1 - file: bitanswer.fil

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.77O RULE 10F-3
<SEQUENCE>2
<FILENAME>firstdart77o.txt
<TEXT>
Document 2 - file: firstdart77o.txt

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.77O RULE 10F-3
<SEQUENCE>3
<FILENAME>jarden77o.txt
<TEXT>
Document 3 - file: jarden77o.txt

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.77O RULE 10F-3
<SEQUENCE>4
<FILENAME>mallin77o.txt
<TEXT>
Document 4 - file: mallin77o.txt

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.77O RULE 10F-3
<SEQUENCE>5
<FILENAME>reynold77o.txt
<TEXT>
Document 5 - file: reynold77o.txt

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.77O RULE 10F-3
<SEQUENCE>6
<FILENAME>toll77o.txt
<TEXT>
Document 6 - file: toll77o.txt

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.77B ACCT LTTR
<SEQUENCE>7
<FILENAME>tax377b.txt
<TEXT>
Document 7 - file: tax377b.txt

</DOCUMENT>
</SEC-DOCUMENT>