<SEC-DOCUMENT>0001209191-16-090224-index.html : 20160106
<SEC-HEADER>0001209191-16-090224.hdr.sgml : 20160106
<ACCEPTANCE-DATETIME>20160106210700
ACCESSION NUMBER:		0001209191-16-090224
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20160104
FILED AS OF DATE:		20160106
DATE AS OF CHANGE:		20160106

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Mast Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001160308
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				841318182
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		3611 VALLEY CENTRE DRIVE
		STREET 2:		SUITE 500
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130
		BUSINESS PHONE:		8585520866

	MAIL ADDRESS:	
		STREET 1:		3611 VALLEY CENTRE DRIVE
		STREET 2:		SUITE 500
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ADVENTRX PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	20030613

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BIOKEYS PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	20010928

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Roberts Brandi
		CENTRAL INDEX KEY:			0001516354

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32157
		FILM NUMBER:		161328668

	MAIL ADDRESS:	
		STREET 1:		12390 EL CAMINO REAL #150
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
Document 1 - file: doc4.html

Document 1 - RAW XML: doc4.xml

</DOCUMENT>
</SEC-DOCUMENT>