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Summary of significant accounting policies (Details 6) (USD $) In Millions, unless otherwise specified | 12 Months Ended | 1 Months Ended | 12 Months Ended
--- | --- | --- | ---
Dec. 31, 2011 | Dec. 31, 2010 | Dec. 31, 2009 | Jan. 31, 2012 Collaborative arrangements Musculoskeletal Transplant Foundation ("MTF") Y | Dec. 31, 2009 Collaborative arrangements Musculoskeletal Transplant Foundation ("MTF") Y
Summary of significant accounting policies |  |  |  |  |
Period of agreement with MTF (in years) |  |  |  |  | 10
Extended Period of existing agreement with MTF (in years) |  |  |  | 5 |
Advertising expense | $ 0.5 | $ 0.6 | $ 0.7 |  |
Income taxes |  |  |  |  |
Unrecognized tax benefits inclusive of interest and penalties | $ 1.2 | $ 1.0 |  |  |

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- Definition Amount charged to advertising expense for the period, which are expenses incurred with the objective of increasing revenue for a specified brand, product or product line. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher AICPA -Name Statement of Position (SOP) -Number 93-7 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 720 -SubTopic 35 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6420018&loc=d3e36677-107848 + Details
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