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Long-term Investments - Additional Information (Detail) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands |  | 12 Months Ended
--- | --- | ---
Mar. 04, 2015 | Dec. 31, 2016 | Dec. 31, 2015
Debt Instrument [Line Items] |  |  |
Fair value of the debt security |  | $ 12,200 |
Unrealized gain (loss) on debt securities |  | 1,744 | $ 3,348
Other-than-temporary impairment on debt securities |  | 2,727 |
Bone Biologics Inc [Member] |  |  |
Investments Equity Securities [Abstract] |  |  |
Value of common stock held |  | $ 2,500 |
Warrants held for share purchases |  | 458 |
Weighted average exercise price of warrant |  | $ 1.18 |
Warrants exercisable period |  | 7 years |
Warrant expiration term |  | between 2020 and 2021 |
Warrants expiration start year |  | 2020 |
Warrants expiration end year |  | 2021 |
eNeura Note [Member] | eNeura Inc [Member] |  |  |
Debt Instrument [Line Items] |  |  |
Non-refundable fees paid | $ 300 |  |
Accrued interest rate on promissory note | 8.00% |  |
Maturity description of Promissory note |  | The eNeura Note will mature on March 4, 2019 |
Debt Instrument, Maturity Date |  | Mar. 04, 2019 |
eNeura Note [Member] | eNeura Inc [Member] | Convertible Debt Securities |  |  |
Debt Instrument [Line Items] |  |  |
Principal amount of promissory note | $ 15,000 |  |
eNeura Note [Member] | eNeura Inc [Member] | Debt Securities [Member] |  |  |
Debt Instrument [Line Items] |  |  |
Unrealized gain (loss) on debt securities |  | $ 1,744 |
eNeura Note [Member] | eNeura Inc [Member] | Preferred Stock [Member] |  |  |
Debt Instrument [Line Items] |  |  |
Conversion price per share |  | $ 7.30 |
eNeura Note [Member] | eNeura Inc [Member] | Minimum [Member] |  |  |
Debt Instrument [Line Items] |  |  |
Third party acquisition |  | 50.00% |

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