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Long-term Investments - Additional Information (Detail) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands |  | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Mar. 04, 2015 | Mar. 31, 2017 | Dec. 31, 2017 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Debt Instrument [Line Items] |  |  |  |  |  |
Fair value of the debt security |  | $ 9,000 | $ 16,100 | $ 16,100 |  |
Unrealized gain (loss) on debt securities |  |  |  | 3,830 | $ (1,744) | $ (3,348)
Amortized cost basis in debt security |  |  | 9,000 | 9,000 |  |
Other-than-temporary impairment on debt securities |  | 5,600 |  | 5,585 | $ 2,727 |
Bone Biologics Inc [Member] |  |  |  |  |  |
Investments Equity Securities [Abstract] |  |  |  |  |  |
Value of common stock held |  |  | $ 2,500 | $ 2,500 |  |
Warrants held for share purchases |  |  | 458 | 458 |  |
Weighted average exercise price of warrant |  |  | $ 1.18 | $ 1.18 |  |
Warrants exercisable period |  |  |  | 7 years |  |
Warrant expiration term |  |  |  | between 2020 and 2021 |  |
Warrants expiration start year |  |  |  | 2020 |  |
Warrants expiration end year |  |  |  | 2021 |  |
eNeura Note [Member] | eNeura Inc [Member] |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |
Non-refundable fees paid | $ 300 |  |  |  |  |
Accrued interest rate on promissory note | 8.00% |  |  |  |  |
Maturity description of Promissory note |  |  |  | The eNeura Note will mature on March 4, 2019 |  |
Debt Instrument, Maturity Date |  |  |  | Mar. 04, 2019 |  |
eNeura Note [Member] | eNeura Inc [Member] | Convertible Debt Securities |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |
Principal amount of promissory note | $ 15,000 |  |  |  |  |
eNeura Note [Member] | eNeura Inc [Member] | Debt Securities [Member] |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |
Unrealized gain (loss) on debt securities |  | $ (3,200) | $ 7,100 |  |  |
eNeura Note [Member] | eNeura Inc [Member] | Preferred Stock [Member] |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |
Conversion price per share |  |  | $ 7.30 | $ 7.30 |  |
eNeura Note [Member] | eNeura Inc [Member] | Minimum [Member] |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |
Third party acquisition |  |  | 50.00% | 50.00% |  |

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