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Milestone achievement period.

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Purchase of stock from related party.

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No definition available.

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Amortized cost of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

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Amount of increase (decrease) in the value of a contingent consideration liability, including, but not limited to, differences arising upon settlement.

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Amount of liability recognized arising from contingent consideration in a business combination.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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No definition available.

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Amount of increase (decrease) of financial instrument classified as an asset measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.

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Represents the quantification of the effect of adopting the new accounting standard or change in accounting principle expected by the entity to have a significant effect on the entity's financial statements.

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Amount of the effect of a change in accounting principle on basic earnings per share.

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The cash outflow associated with the purchase of all investments (debt, security, other) during the period.

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Fair Value Measurements - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands		2 Months Ended	3 Months Ended	6 Months Ended
	Apr. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Jun. 30, 2018	Dec. 31, 2017	Jun. 30, 2017	Dec. 31, 2016
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Amortized cost basis in debt security		$ 9,000		$ 9,000
Spinal Kinetics [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Future milestone payments	$ 60,000
Milestone achievement period	5 years
Contingent consideration	$ 25,491	26,600		26,600
Other Expense [Member] \| Spinal Kinetics [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Increase in the fair value of a contingent consideration		1,100
Maximum [Member] \| Spinal Kinetics [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Future milestone payments	60,000
US Food And Drug Administration [Member] \| Spinal Kinetics [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Future milestone payments	15,000
Revenue Milestone [Member] \| Spinal Kinetics [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Future milestone payments	$ 45,000
Debt Securities [Member] \| Fair Value, Inputs, Level 3 [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair value of debt securities		$ 18,010		18,010	$ 16,050	$ 9,000	$ 12,220
Increase in estimated fair value of the debt security				$ 2,000
Bone Biologics Inc [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Purchase of common stock, value			$ 500
Bone Biologics Inc [Member] \| Common Stock [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Purchase of stock, shares			250,000
ASU 2016-01 [Member] \| Bone Biologics Inc [Member] \| Equity Investments [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Increase in previously recorded value of equity investments resulted from new measurement			$ 1,600
Impact on remeasurement of equity investments per share before taxes included within other income or expense			$ 0.09