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Fair Value Measurements and Investments - Schedule of Reconciliation of Debt Security and Warrant (Detail) - eNeura Inc [Member] - Debt Security and Warrant [Member] - Fair Value, Inputs, Level 3 [Member] - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]    
Beginning balance $ 17,820 $ 16,050
Gains or losses recorded for the period    
Recognized in other comprehensive income (loss) (2,593) 3,200
Change in classification of debt security to held to maturity (15,227) 0
Issuance of Warrant as consideration for extension 491 0
Impairment of Warrant (491) 0
Ending balance $ 0 $ 19,250