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Fair Value Measurements and Investments - Additional Information (Detail) SFr in Millions |  |  | 1 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | --- | ---
Oct. 01, 2020 USD ($) | Apr. 30, 2018 USD ($) | Nov. 30, 2021 USD ($) | Oct. 01, 2019 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Oct. 10, 2021 USD ($) | Oct. 10, 2021 CHF (SFr) | Oct. 01, 2020 CHF (SFr)
Spinal Kinetics [Member] |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Milestone achievement period |  | 5 years |  |  | 12 months |  |  |  |
Contingent consideration |  |  |  |  | $ 17,200,000 |  |  |  |
Payment for contingent consideration liability |  |  |  |  | 30,000,000.0 |  |  |  |
Spinal Kinetics [Member] | Other Current Liabilities |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Contingent consideration |  |  |  |  | 17,200,000 |  |  |  |
Maximum [Member] | Spinal Kinetics [Member] |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Future milestone payments |  | $ 60,000,000.0 |  |  |  |  |  |  |
US Food And Drug Administration [Member] | Spinal Kinetics [Member] |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Future milestone payments |  | 15,000,000.0 |  |  |  |  |  |  |
Revenue Milestone [Member] |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Future milestone payments |  |  |  |  | 15,000,000.0 |  |  |  |
Revenue Milestone [Member] | Spinal Kinetics [Member] |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Future milestone payments |  | $ 45,000,000.0 |  |  |  |  |  |  |
eNeura Inc [Member] |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Payments of debt security |  |  |  | $ 4,000,000.0 |  |  |  |  |
Other-than-temporary impairment on debt securities |  |  |  | 6,500,000 |  |  |  |  |
eNeura Inc [Member] | Reclassification Out of Accumulated Other Comprehensive Income (Loss) [Member] |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Unrealized gains on debt securities |  |  |  | $ 5,200,000 |  |  |  |  |
Equity Warrants | Bone Biologics Inc [Member] |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Impairment charges on investment |  |  |  |  |  | $ 200,000 |  |  |
Neo Medical [Member] |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Convertible loans |  |  |  |  |  |  | $ 700,000 | SFr 0.6 | SFr 4.6
Convertible loans interest rate |  |  |  |  |  |  |  |  | 8.00%
Maturity date | Oct. 01, 2024 |  |  |  |  |  |  |  |
Convertible loan credit losses |  |  |  |  | 0 |  |  |  |
Neo Medical [Member] | Other Income [Member] |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Unrealized gain (loss) on equity investments |  |  | $ 400,000 |  |  |  |  |  |
Preferred Stock [Member] | Neo Medical [Member] |  |  |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |
Amount of Preferred stock consideration | $ 5,000,000.0 |  |  |  |  |  |  |  |
Unrealized gain (loss) on equity investments |  |  |  |  | $ 336,000 |  |  |  |

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