Net Loss Per Share

9 Months Ended

Sep. 30, 2022

Basic and diluted net loss per share attributable to ordinary shareholders was calculated as follows (in thousands, except share and per share amounts):


	Three Months Ended September 30,				Nine Months Ended September 30,
	2022		2021		2022		2021
Numerator
Net loss	$	(18,371)	$	(15,849)	$	(60,579)	$	(46,092)
Net loss attributable to ordinary shareholders - basic and diluted	$	(18,371)	$	(15,849)	$	(60,579)	$	(46,092)

Denominator
Weighted-average number of ordinary shares used in net loss per share - basic and diluted	42,525,855		41,708,220		42,377,895		39,378,824
Net loss per share - basic and diluted	$	(0.43)	$	(0.38)	$	(1.43)	$	(1.17)

The Company’s potentially dilutive securities, which include unvested ordinary shares, unvested restricted share units, and options granted, have been excluded from the computation of diluted net loss per share as the effect would be to reduce the net loss per share. Therefore, the weighted-average number of ordinary shares outstanding used to calculate both basic and diluted net loss per share attributable to ordinary shareholders is the same. The Company excluded the following potential ordinary shares, presented based on amounts outstanding at each period end, from the computation of diluted net loss per share attributable to ordinary shareholders for the three months and nine months ended September 30, 2022 and 2021 because including them would have had an anti-dilutive effect:


	Three Months Ended September 30,		Nine Months Ended September 30,
	2022	2021	2022	2021
Unvested restricted share units	226,395	160,595	226,395	160,595
Vested restricted share units, for which shares are not in issue	17,112	44,280	17,112	44,280
Share options	5,035,923	4,092,496	5,035,923	4,092,496
	5,279,430	4,297,371	5,279,430	4,297,371