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Share-based Compensation - Share Options (Details) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended
Sep. 30, 2022
Dec. 31, 2021
Sep. 30, 2022
Sep. 30, 2021
Number of Shares        
Granted (in shares)     2,000,783  
Exercised (in shares)     (461,772)  
Forfeited (in shares)     (418,591)  
Outstanding, ending balance (in shares) 5,035,923   5,035,923  
Exercisable (in shares) 2,106,737   2,106,737  
Unvested (in shares) 2,929,746   2,929,746  
Weighted Average Exercise Price        
Outstanding, beginning balance (in dollars per share)     $ 13.53  
Granted (in dollars per share)     13.86  
Exercised (in dollars per share)     0.77  
Forfeited (in dollars per share)     9.38  
Outstanding, ending balance (in dollars per share) $ 14.28 $ 13.53 14.28  
Exercisable (in dollars per share) 7.07   7.07  
Unvested (in dollars per share) $ 16.68   $ 16.68  
Weighted Average Remaining Contractual Term (Years)        
Outstanding balance (in years) 8 years 7 months 6 days 8 years 7 months 20 days    
Exercisable (in years) 7 years 9 months 25 days      
Unvested (in years) 9 years 1 month 28 days      
Outstanding, aggregate intrinsic value $ 17,846 $ 51,162 $ 17,846  
Exercisable, aggregate intrinsic value 15,544   15,544  
Unvested, aggregate intrinsic value 2,302   2,302  
Aggregate intrinsic value of options exercised during the period     $ 5,500 $ 41,800
Granted (in dollars per share)     $ 10.29 $ 22.71
Unrecognized compensation cost of options $ 30,700   $ 30,700 $ 27,600
Vested restricted share units, for which shares are not in issue        
Weighted Average Remaining Contractual Term (Years)        
Period for recognition (in years)     2 years 11 months 19 days 3 years 2 months 12 days
Vested restricted share units, for which shares are not in issue | Ordinary shares        
Number of Shares        
Outstanding, beginning balance (in shares)     3,915,503  
Outstanding, ending balance (in shares)   3,915,503