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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (24,208) $ (21,171)
Adjustments to reconcile net loss to net cash used in operating activities    
Depreciation and amortization 48 54
Non-cash gain on foreign currency remeasurement (2,107) (219)
Non-cash share-based compensation 4,071 3,128
Non-cash lease expenses 539 550
Changes in operating assets and liabilities    
Prepaid expenses and other current assets (1,484) (1,386)
Deferred and prepaid tax assets 129 (135)
Other assets (44) (311)
Operating lease liabilities (478) (538)
Accounts payable (973) (445)
Accrued expenses and other liabilities (3,216) (2,650)
Net cash used in operating activities (27,723) (23,123)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchases of property and equipment (29) (82)
Net cash used in investing activities (29) (82)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from issuance of ordinary shares, net of issuance costs 1,188 0
Payments of tax withholding on stock award (109) 0
Proceeds from exercise of share options 0 189
Net cash provided by financing activities 1,079 189
Effect of exchange rate changes on cash, cash equivalents and restricted cash 666 (6,543)
Net decrease in cash, cash equivalents and restricted cash (26,007) (29,559)
Cash, cash equivalents and restricted cash, beginning of the period 143,381 273,347
Cash, cash equivalents and restricted cash, end of the period 117,374 243,788
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:    
Right of use assets obtained in exchange for new operating lease liabilities 92 0
Proceeds from exercise of options received and recorded in other current assets 0 208
Deferred issuance costs included in accrued expenses 0 835
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Abstract]    
Cash and cash equivalents 117,103 243,684
Restricted cash 271 104
Total cash, cash equivalents and restricted cash $ 117,374 $ 243,788