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Consolidated Statements of Stockholders' Equity (Deficit) - USD ($) $ in Thousands | Total | April 2018 Public Offering | November 2018 Public Offering | Common Stock $0.001 par value | Common Stock $0.001 par value November 2018 Public Offering | Common Stock | Common Stock April 2018 Public Offering | Additional Paid-In Capital | Additional Paid-In Capital November 2018 Public Offering | Accumulated Deficit | Accumulated Other Comprehensive Income (Loss)
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning Balance at Dec. 31, 2016 | $ (3,444) |  |  |  |  | $ 30,897 |  | $ 5,732 |  | $ (38,345) | $ (1,728)
Beginning Balance, Shares at Dec. 31, 2016 |  |  |  |  |  | 16,926,120 |  |  |  |  |
Proceeds from the issuance of common stock and accompanying warrants in public offering | 9,187 |  |  |  |  | $ 9,187 |  |  |  |  |
Proceeds from the issuance of common stock and accompanying warrants in public offering, Shares |  |  |  |  |  | 1,311,000 |  |  |  |  |
Issuance of common stock and warrants in private placement | 11,691 |  |  |  |  | $ 11,691 |  |  |  |  |
Issuance of common stock and warrants in private placement, Shares |  |  |  |  |  | 1,446,016 |  |  |  |  |
Fair value of warrants issued in connection with the December 2017 financing classified as derivative financial instruments | (3,017) |  |  |  |  | $ (3,017) |  |  |  |  |
Share issuance costs | (1,321) |  |  |  |  | (1,321) |  |  |  |  |
Stock-based compensation expense | 1,719 |  |  |  |  |  |  | 1,719 |  |  |
Proceeds from the exercise of stock options and warrants | 2,588 |  |  |  |  | $ 2,588 |  |  |  |  |
Proceeds from the exercise of stock options and warrants, Shares |  |  |  |  |  | 492,826 |  |  |  |  |
Settlement of vested restricted stock units, net of taxes, Shares |  |  |  |  |  | 2,264 |  |  |  |  |
Reclassification of exercised compensation stock options and warrants from additional paid-in capital |  |  |  |  |  | $ 849 |  | (849) |  |  |
Reclassification of liability classified warrants upon exercise | $ 1,356 |  |  |  |  | 1,356 |  |  |  |  |
Proceeds from exercise of stock options | 173,500 |  |  |  |  |  |  |  |  |  |
Net loss | $ (28,024) |  |  |  |  |  |  |  |  | (28,024) |
Foreign currency translation adjustments | 1,775 |  |  |  |  |  |  |  |  |  | 1,775
Ending Balance at Dec. 31, 2017 | (7,490) |  |  |  |  | $ 52,230 |  | 6,602 |  | (66,369) | 47
Ending Balance, Shares at Dec. 31, 2017 |  |  |  |  |  | 20,178,226 |  |  |  |  |
Proceeds from the issuance of common stock and accompanying warrants in public offering |  | $ 18,400 | $ 20,126 |  | $ 3 |  | $ 18,400 |  | $ 20,123 |  |
Proceeds from the issuance of common stock and accompanying warrants in public offering, Shares |  |  |  |  | 2,439,394 |  | 2,463,185 |  |  |  |
Fair value of liability-classified warrants issued in connection with April 2018 public offering | (7,372) |  |  |  |  | $ (7,372) |  |  |  |  |
Share issuance costs |  | $ (1,273) | (1,867) |  |  |  | $ (1,273) |  | (1,867) |  |
Stock-based compensation expense | 1,047 |  | $ 849 |  |  |  |  | 1,047 | $ 849 |  |
Proceeds from the exercise of stock options and warrants | 4,637 |  |  |  |  | $ 4,637 |  |  |  |  |
Proceeds from the exercise of stock options and warrants, Shares |  |  |  |  |  | 736,130 |  |  |  |  |
Settlement of vested restricted stock units, net of taxes | (2) |  |  |  |  |  |  | (2) |  |  |
Settlement of vested restricted stock units, net of taxes, Shares |  |  |  |  |  | 705 |  |  |  |  |
Reclassification of exercised compensation stock options and warrants from additional paid-in capital |  |  |  |  |  | $ 110 |  | (110) |  |  |
Reclassification of liability classified warrants upon exercise | 3,748 |  |  |  |  | 3,748 |  |  |  |  |
Reclassification of April 2016 compensation options and warrants from additional paid-in capital to derivative financial instruments due to change in functional currency | (1,586) |  |  |  |  |  |  | (1,586) |  |  |
Reclassification of USD denominated warrants from derivative financial instruments to additional paid-in capital due to change in functional currency | 2,478 |  |  |  |  |  |  | 2,478 |  |  |
Reclassification of equity-classified stock options to stock-based compensation liability due to change in functional currency | (4,182) |  |  |  |  |  |  | (4,182) |  |  |
Reclassification from stock-based compensation liability to common stock as a result of exercise of stock options | 32 |  |  |  |  | 32 |  |  |  |  |
Reclassification of non-employee options recorded as derivative financial instruments due to modification of options | 1,206 |  |  |  |  |  |  | 1,206 |  |  |
Reclassification of stock-based compensation due to modification of options | 10,338 |  |  |  |  |  |  | 10,338 |  |  |
Reclassification upon change in corporate domicile |  |  |  | $ 23 |  | $ (70,512) |  | 70,489 |  |  |
Reclassification upon change in corporate domicile, shares |  |  |  | 23,378,246 |  | (23,378,246) |  |  |  |  |
Proceeds from exercise of stock options | $ 26 |  |  |  |  |  |  | 26 |  |  |
Proceeds from exercise of stock options | 98,500 |  |  | 10,220 |  |  |  |  |  |  |
Net loss | $ (28,623) |  |  |  |  |  |  |  |  | (28,623) |
Foreign currency translation adjustments | (638) |  |  |  |  |  |  |  |  |  | (638)
Ending Balance at Dec. 31, 2018 | $ 9,854 |  |  | $ 26 |  |  |  | $ 105,411 |  | $ (94,992) | $ (591)
Ending Balance, Shares at Dec. 31, 2018 |  |  |  | 25,827,860 |  |  |  |  |  |  |

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- Definition Total of all stockholders' equity (deficit) items, net of receivables from officers, directors, owners, and affiliates of the entity which are attributable to the parent. The amount of the economic entity's stockholders' equity attributable to the parent excludes the amount of stockholders' equity which is allocable to that ownership interest in subsidiary equity which is not attributable to the parent (noncontrolling interest, minority interest). This excludes temporary equity and is sometimes called permanent equity. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 310 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SAB Topic 4.E) -URI http://asc.fasb.org/extlink&oid=27010918&loc=d3e74512-122707 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(31)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(30)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
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Period Type: | instant