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Related Party Transactions - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Apr. 30, 2016
Mar. 31, 2018
Dec. 31, 2018
Dec. 31, 2017
Related Party Transaction [Line Items]        
Consulting fee owed to directors     $ 8,000  
Change in fair value of derivative financial instruments     (3,577,000) $ (3,443,000)
Non-employee Stock Options        
Related Party Transaction [Line Items]        
Change in fair value of derivative financial instruments     $ 300,000 (400,000)
Minimum | A&B (HK) Company Ltd.        
Related Party Transaction [Line Items]        
Ownership percentage of shares outstanding     5.00%  
Directors        
Related Party Transaction [Line Items]        
Consulting fees paid     $ 33,000 16,000
Montel Media, Inc. | Minimum        
Related Party Transaction [Line Items]        
Beneficially owns common stock percentage   5.00%    
Montel Media, Inc. | Consulting Agreement        
Related Party Transaction [Line Items]        
Consulting fees paid     45,000 200,000
Consulting monthly fee $ 15,000      
Clinvue LLC        
Related Party Transaction [Line Items]        
Consulting fees paid     $ 100,000 $ 100,000
CEO        
Related Party Transaction [Line Items]        
Ownership percentage of shares outstanding     5.00%  
CFO/CEO        
Related Party Transaction [Line Items]        
Ownership percentage of shares outstanding     5.00%  
Director 1        
Related Party Transaction [Line Items]        
Ownership percentage of shares outstanding     5.00%  
Director 2        
Related Party Transaction [Line Items]        
Ownership percentage of shares outstanding     5.00%