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Share Based Payments (Tables)

12 Months Ended

Dec. 31, 2020

Summary of Stock Option Activity

The following is a summary of stock option activity for the year ended December 31, 2020 and 2019:

						Weighted Average
						Remaining				Weighted Average				Aggregate
						Contractual				Exercise Price				Intrinsic Value
		Number of Options				Life (in years)				in USD$				in USD$
Outstanding as of December 31, 2018			94,475				5.16			$	249.87			$	8,308
Granted			33,337								162.74
Forfeited			(13,939	)							298.55
Exercised (1)			(14,855	)							96.95
Outstanding as of December 31, 2019			99,018				7.78			$	236.63			$	—
Granted			42,988							$	15.20
Forfeited/Cancelled			(28,448	)							210.57
Exercised			—								—
Outstanding as of December 31, 2020			113,558				7.75			$	159.33			$	—
Exercisable as of December 31, 2020			57,725				6.56			$	117.90			$	—
(1) For the year ended December 31, 2019, 14,855 stock options were exercised on a cashless basis resulting in 13,818 shares being withheld in satisfaction of the exercise price.

Summary of Company's Restricted Stock Unit Activity

The following is a summary of the Company’s RSU activity for the years ended December 31, 2020 and 2019:

		Number of Restricted Stock Units				Weighted Average Grant Date Fair Value per Unit
Outstanding as of December 31, 2018			27			CAD$350.00
Granted			788			USD$21.17
Vested and settled during 2019 (1)			(27	)		CAD$350.00
Outstanding as of December 31, 2019			788			USD$21.17
Granted			7,172			USD$15.25
Settled during 2020			(7,792	)		USD$17.81
Outstanding as of December 31, 2020			168			USD$13.20
(1) Includes 7 RSUs withheld to satisfy required withholding taxes.

Summary of Stock-Based Compensation Expense is Classified in Condensed Consolidated Statements of Operations and Comprehensive Loss

Stock-Based Compensation Expense

Stock-based compensation expense is classified in the Company’s consolidated statements of operations and comprehensive loss as follows (amounts in thousands):

		2020				2019
Research and development		$	933			$	898
Cost of sales		$	(1	)			—
General and administrative			1,597				3,793
Total		$	2,529			$	4,691

Employee and Director Stock Options

Estimation Using Black-Scholes Option Pricing Model With Following Weighted Average Assumptions

The fair value of employee and director stock options granted for the years ended December 31, 2020 and 2019 had a weighted average grant date fair value of $9.71 and $105.38 per option, respectively, and they were estimated using the Black-Scholes option-pricing model with the following weighted-average assumptions:

		Year Ended December 31,
		2020				2019
Stock price		$15.23				$162.74
Exercise price		$15.23				$162.74
Expected term		5.32 years				5.42 years
Expected volatility			75.35	%			76.90	%
Risk-free interest rate			0.52	%			1.96	%
Dividend rate			0.00	%			0.00	%

Consultants Stock Options

Estimation Using Black-Scholes Option Pricing Model With Following Weighted Average Assumptions

Stock options granted to the Company’s consultants for the year ended December 31, 2020 had a weighted average grant date fair value of $8.18 per share, and they were estimated using the Black-Scholes option-pricing model with the following weighted-average assumptions:

		Year Ended December 31,
		2020
Stock price		$13.58
Exercise price		$13.58
Option term		5.27 years
Expected volatility			73.15	%
Risk-free interest rate			0.33	%
Dividend rate			0.00	%

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