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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Revenue:    
Total operating revenue $ 661 $ 1,496
Cost of sales:    
Cost of product sales $ 388 $ 846
Type of Cost, Good or Service [Extensible List] us-gaap:ProductMember us-gaap:ProductMember
Gross profit $ 273 $ 650
Operating expenses:    
Research and development 4,582 8,061
Selling, general and administrative 9,714 16,521
Amortization expense 363 64
Total operating expenses 14,659 24,646
Operating loss (14,386) (23,996)
Other income:    
Other income 63 95
Change in fair value of derivative financial instruments 4 14,113
Foreign exchange gain 189 7
Total other income 256 14,215
Net loss (14,130) (9,781)
Other comprehensive loss:    
Foreign currency translation adjustments (197) (311)
Comprehensive loss $ (14,327) $ (10,092)
Net loss per share    
Basic $ (11.80) $ (12.99)
Diluted $ (11.80) $ (12.99)
Weighted average shares outstanding    
Basic 1,197,774 752,932
Diluted 1,197,774 752,932
Product Sales    
Revenue:    
Total operating revenue $ 625 $ 1,454
Fee Revenue    
Revenue:    
Total operating revenue 9 37
License Revenue    
Revenue:    
Total operating revenue $ 27 $ 5